Liquid biopsies in cancer diagnosis, monitoring, and prognosis

G De Rubis, SR Krishnan, M Bebawy - Trends in pharmacological sciences, 2019 - cell.com
Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

A review of cyclic olefin copolymer applications in microfluidics and microdevices

A Agha, W Waheed, N Alamoodi… - Macromolecular …, 2022 - Wiley Online Library
Cyclic olefin copolymers (COC) are amorphous, transparent thermoplastics composed of
cyclic olefin monomers (norbornene) and linear olefins (ethene). They are increasingly …

Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Circulating tumor cells in precision oncology: clinical applications in liquid biopsy and 3D organoid model

C Yang, BR **a, WL **, G Lou - Cancer Cell International, 2019 - Springer
Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with
solid tumors, which function as a seed for metastases. Cancer cells metastasize through the …

A review of active and passive hybrid systems based on Dielectrophoresis for the manipulation of microparticles

A Al-Ali, W Waheed, E Abu-Nada, A Alazzam - Journal of Chromatography …, 2022 - Elsevier
Particle separation is essential in a broad range of systems and has several biological
applications. Microfluidics has emerged as a potentially transformational method for particle …

Microfluidics for neuronal cell and circuit engineering

R Habibey, JE Rojo Arias, J Striebel… - Chemical …, 2022 - ACS Publications
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

The role of dielectrophoresis for cancer diagnosis and prognosis

GI Russo, N Musso, A Romano, G Caruso, S Petralia… - Cancers, 2021 - mdpi.com
Simple Summary Dielectrophoresis (DEP) is a label-free cell manipulation technique based
on electrical differences that can be applied to liquid biopsies in the context of cancer …

Microfluidics for label-free sorting of rare circulating tumor cells

S Zhu, F Jiang, Y Han, N **ang, Z Ni - Analyst, 2020 - pubs.rsc.org
Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

Dielectrophoretic manipulation of cancer cells and their electrical characterization

I Turcan, MA Olariu - ACS Combinatorial Science, 2020 - ACS Publications
Electromanipulation and electrical characterization of cancerous cells is becoming a topic of
high interest as the results reported to date demonstrate a good differentiation among …