Myelination-independent functions of oligodendrocyte precursor cells in health and disease

Y **ao, T Czopka - Nature neuroscience, 2023 - nature.com
Oligodendrocyte precursor cells (OPCs) are a population of tissue-resident glial cells found
throughout the CNS, constituting approximately 5% of all CNS cells and persisting from …

The biology of regeneration failure and success after spinal cord injury

AP Tran, PM Warren, J Silver - Physiological reviews, 2018 - journals.physiology.org
Since no approved therapies to restore mobility and sensation following spinal cord injury
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …

Motor skill learning requires active central myelination

IA McKenzie, D Ohayon, H Li, J Paes de Faria, B Emery… - science, 2014 - science.org
Myelin-forming oligodendrocytes (OLs) are formed continuously in the healthy adult brain. In
this work, we study the function of these late-forming cells and the myelin they produce …

NG 2‐glia and their functions in the central nervous system

L Dimou, V Gallo - Glia, 2015 - Wiley Online Library
In the central nervous system, NG2‐glia represent a neural cell population that is distinct
from neurons, astrocytes, and oligodendrocytes. While in the past the main role ascribed to …

[HTML][HTML] Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination

A Barateiro, A Fernandes - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Oligodendrocytes are neuroglial cells responsible, within the central nervous system, for
myelin sheath formation that provides an electric insulation of axons and accelerate the …

Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2

D Sakry, A Neitz, J Singh, R Frischknecht… - PLoS …, 2014 - journals.plos.org
The role of glia in modulating neuronal network activity is an important question.
Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane …

NG2 cells: Properties, progeny and origin

J Trotter, K Karram, A Nishiyama - Brain research reviews, 2010 - Elsevier
The NG2 proteoglycan is a type 1-transmembrane protein expressed by a range of cell types
within and outside the mammalian nervous system. NG2-expressing (NG2) cells are found …

Origin, lineage and function of cerebellar glia

A Buffo, F Rossi - Progress in neurobiology, 2013 - Elsevier
The glial cells of the cerebellum, and particularly astrocytes and oligodendrocytes, are
characterized by a remarkable phenotypic variety, in which highly peculiar morphological …

The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury

GJ Duncan, SB Manesh, BJ Hilton, P Assinck… - Glia, 2020 - Wiley Online Library
Oligodendrocyte progenitor cells (OPCs) are the most proliferative and dispersed population
of progenitor cells in the adult central nervous system, which allows these cells to rapidly …

Oligodendrocyte development and myelination in neurodevelopment: molecular mechanisms in health and disease

A Barateiro, D Brites… - Current pharmaceutical …, 2016 - ingentaconnect.com
Oligodendrocytes are the myelinating cells of the central nervous system that constitute
about 5 to 10% of the total glial population. These cells are responsible for myelin sheath …