Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
Glutamate receptor ion channels: structure, regulation, and function
The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
Mechanism and health effects of heavy metal toxicity in humans
GA Engwa, PU Ferdinand, FN Nwalo… - Poisoning in the …, 2019 - books.google.com
Several heavy metals are found naturally in the earth crust and are exploited for various
industrial and economic purposes. Among these heavy metals, a few have direct or indirect …
industrial and economic purposes. Among these heavy metals, a few have direct or indirect …
Structure, function, and allosteric modulation of NMDA receptors
NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca2+-
permeable component of excitatory neurotransmission in the central nervous system (CNS) …
permeable component of excitatory neurotransmission in the central nervous system (CNS) …
(Un) suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions–a review
The use of buffers to maintain the pH within a desired range is a very common practice in
chemical, biochemical and biological studies. Among them, zwitterionic N-substituted …
chemical, biochemical and biological studies. Among them, zwitterionic N-substituted …
Molecular basis of NMDA receptor functional diversity
P Paoletti - European Journal of Neuroscience, 2011 - Wiley Online Library
NMDA receptors (NMDARs) form glutamate‐gated ion channels widely expressed in the
central nervous system and highly permeable to calcium ions. NMDARs have always …
central nervous system and highly permeable to calcium ions. NMDARs have always …
Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential
N‐methyl‐D‐aspartate receptors (NMDARs) are ion channels gated by glutamate, the major
excitatory neurotransmitter in the mammalian central nervous system (CNS). They are …
excitatory neurotransmitter in the mammalian central nervous system (CNS). They are …
Zinc at glutamatergic synapses
P Paoletti, AM Vergnano, B Barbour, M Casado - Neuroscience, 2009 - Elsevier
It has long been known that the mammalian forebrain contains a subset of glutamatergic
neurons that sequester zinc in their synaptic vesicles. This zinc may be released into the …
neurons that sequester zinc in their synaptic vesicles. This zinc may be released into the …
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates
NJ Sullivan, TW Geisbert, JB Geisbert, L Xu, Z Yang… - Nature, 2003 - nature.com
Containment of highly lethal Ebola virus outbreaks poses a serious public health challenge.
Although an experimental vaccine has successfully protected non-human primates against …
Although an experimental vaccine has successfully protected non-human primates against …
NMDA receptors in the central nervous system
NMDA-type glutamate receptors are ligand-gated ion channels that mediate a major
component of excitatory neurotransmission in the central nervous system (CNS). They are …
component of excitatory neurotransmission in the central nervous system (CNS). They are …