Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular
mechanisms involved in the regulation of conventional outflow resistance and thus …

The major drainage structures for aqueous humor (AH) are the conventional or trabecular
outflow pathways, which are comprised of the trabecular meshwork (made up by the uveal …

With the combined purpose of facilitating useful vision over a lifetime, a number of ocular
cells have evolved specialized features not found elsewhere in the body. The trabecular …

Increased intraocular pressure (IOP) represents a major risk factor for glaucoma, a prevalent
eye disease characterized by death of retinal ganglion cells; lowering IOP is the only proven …

Ocular regenerative therapies are on track to revolutionize treatment of numerous blinding
disorders, including corneal disease, cataract, glaucoma, retinitis pigmentosa, and age …

Glaucoma is a blinding optic neuropathy, the main risk factor for which is increased
intraocular pressure (IOP). The trabecular meshwork, located within the iridocorneal angle …

The contrast sensitivity function (CSF) predicts functional vision better than acuity, but long
testing times prevent its psychophysical assessment in clinical and practical applications …

Glaucoma is the leading cause of global irreversible blindness, necessitating research for
new, more efficacious treatment options than currently exist. Trabecular meshwork (TM) cells …

Background Glaucoma is a group of optic neuropathies in which damage to the optic nerve
results in a distinctive pattern of irreversible vision loss. Elevations in the intraocular …

Glaucoma, a leading cause of blindness worldwide, is characterized by progressive optic
nerve damage, usually associated with intraocular pressure. Although the clinical …