Current state of modeling human psychiatric disorders using zebrafish

FV Costa, TO Kolesnikova, DS Galstyan… - International Journal of …, 2023 - mdpi.com
Psychiatric disorders are highly prevalent brain pathologies that represent an urgent, unmet
biomedical problem. Since reliable clinical diagnoses are essential for the treatment of …

Unlocking the potential of zebrafish research with artificial intelligence: Advancements in tracking, processing, and visualization

YL Fan, FR Hsu, Y Wang, LD Liao - Medical & Biological Engineering & …, 2023 - Springer
Zebrafish have become a widely accepted model organism for biomedical research due to
their strong cortisol stress response, behavioral strain differences, and sensitivity to both …

Exploring the use of deep learning models for accurate tracking of 3D zebrafish trajectories

YL Fan, CH Hsu, FR Hsu, LD Liao - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Zebrafish are ideal model organisms for various fields of biological research, including
genetics, neural transmission patterns, disease and drug testing, and heart disease studies …

Zebrafish models for studying cognitive enhancers

TO Kolesnikova, KA Demin, FV Costa… - Neuroscience & …, 2024 - Elsevier
Cognitive decline is commonly seen both in normal aging and in neurodegenerative and
neuropsychiatric diseases. Various experimental animal models represent a valuable tool to …

Deep learning dives: Predicting anxiety in zebrafish through novel tank assay analysis

A Muralidharan, A Swaminathan, A Poulose - Physiology & Behavior, 2024 - Elsevier
Behavior is fundamental to neuroscience research, providing insights into the mechanisms
underlying thoughts, actions and responses. Various model organisms, including mice, flies …

Towards zebrafish models of CNS channelopathies

TO Kolesnikova, KA Demin, FV Costa… - International Journal of …, 2022 - mdpi.com
Channelopathies are a large group of systemic disorders whose pathogenesis is associated
with dysfunctional ion channels. Aberrant transmembrane transport of K+, Na+, Ca2+ and …

A novel open-access artificial-intelligence-driven platform for CNS drug discovery utilizing adult zebrafish

DA Lukovikov, TO Kolesnikova, AN Ikrin… - Journal of neuroscience …, 2024 - Elsevier
Background Although zebrafish are increasingly utilized in biomedicine for CNS disease
modelling and drug discovery, this generates big data necessitating objective, precise and …

Towards experimental models of delirium utilizing zebrafish

GO Maslov, KN Zabegalov, KA Demin… - Behavioural Brain …, 2023 - Elsevier
Delirium is an acute neuropsychiatric syndrome characterized by impaired behavior and
cognition. Although the syndrome has been known for millennia, its CNS mechanisms and …

Acute behavioral and Neurochemical Effects of Novel N-Benzyl-2-Phenylethylamine Derivatives in Adult Zebrafish

KA Demin, OV Kupriyanova, VA Shevyrin… - ACS Chemical …, 2022 - ACS Publications
Hallucinogenic drugs potently affect brain and behavior and have also recently emerged as
potentially promising agents in pharmacotherapy. Complementing laboratory rodents, the …

Anxiety in aquatics: Leveraging machine learning models to predict adult zebrafish behavior

V Srivastava, A Muralidharan, A Swaminathan… - Neuroscience, 2025 - Elsevier
Accurate analysis of anxiety behaviors in animal models is pivotal for advancing
neuroscience research and drug discovery. This study compares the potential of …