Diabetes remains an important health issue as more patients with chronic and uncontrolled
diabetes develop diabetic nephropathy (DN), which classically presents with proteinuria …

Background Reduced glomerular filtration rate (GFR) in the absence of albuminuria is a
common manifestation of chronic kidney disease (CKD) in diabetes. However, the frequency …

Objectives Type 2 diabetes mellitus (T2DM) imposes a great burden on healthcare systems,
and these patients experience higher long-term risks for develo** end-stage renal …

During the progression of diabetic kidney disease (DKD), renal lactate metabolism is
rewired. The relationship between alterations in renal lactate metabolism and renal fibrosis …

Previous studies showed that statins reduce the progression of kidney function decline and
proteinuria, but whether specific types of statins are more beneficial than others remains …

Aims/hypothesis Some studies have reported that annual change in eGFR (eGFR slope) is
associated with the future risk of end-stage kidney disease, cardiovascular disease and …

We evaluated whether genetic information could offer improvement on risk prediction of
diabetic nephropathy (DN) while adding susceptibility variants into a risk prediction model …

Aims To investigate risk factors for declining renal function among subjects with type-1-
diabetes. Methods Observational study based on data from the diabetes registry DPV. 4424 …

Introduction The aim of the study was to examine whether biomarkers of oxidative stress are
predictors of diabetic nephropathy (DN) progression. Methods The study involved 45 …

Background. Identifying trajectories of kidney disease progression in chronic kidney disease
(CKD) patients may help to deliver better care. We aimed to identify and characterize …