In this opinion, we highlight agent-based modeling as a key tool for exploration of cell–cell
and cell–environment interactions that drive cancer progression, therapeutic resistance, and …

Living materials, which are made either of or by living cells, or are synthetic materials with
programmable elements catered to cells, are environmentally responsive and can self …

Background Hepatocellular carcinoma (HCC) is the most common form of primary liver
cancer and is the third-leading cause of cancer-related death worldwide. Most patients with …

Multiple myeloma (MM) is an osteolytic malignancy that is incurable due to the emergence of
treatment resistant disease. Defining how, when and where myeloma cell intrinsic and …

Building on a strong foundation of philosophy, theory, methods and computation over the
past three decades, Bayesian approaches are now an integral part of the toolkit for most …

Cells are fundamental units of life, constantly interacting and evolving as dynamical systems.
While recent spatial multi-omics can quantitate individual cells' characteristics and …

Glioblastoma multiforme (GBM) is the most aggressive type of glioma and is often resistant
to traditional therapies. Evidence suggests that glioma stem cells (GSCs) contribute to this …

Computational models are not just appealing because they can simulate and predict the
development of biological phenomena across multiple spatial and temporal scales, but also …

Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically
engineered viruses to target, infect and kill cancer cells. Unfortunately, this form of therapy is …

Glioblastoma is the most common and deadliest brain tumour in adults, with a median
survival of 15 months under the current standard of care. Immunotherapies like immune …