MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation

Z Pang, Y Lu, G Zhou, F Hui, L Xu, C Viau… - Nucleic Acids …, 2024‏ - academic.oup.com
We introduce MetaboAnalyst version 6.0 as a unified platform for processing, analyzing, and
interpreting data from targeted as well as untargeted metabolomics studies using liquid …

Current approaches and outstanding challenges of functional annotation of metabolites: a comprehensive review

QH Nguyen, H Nguyen, EC Oh… - Briefings in …, 2024‏ - academic.oup.com
Metabolite profiling is a powerful approach for the clinical diagnosis of complex diseases,
ranging from cardiometabolic diseases, cancer, and cognitive disorders to respiratory …

Gestational diabetes mellitus: Impacts on fetal neurodevelopment, gut dysbiosis, and the promise of precision medicine

M Biete, S Vasudevan - Frontiers in Molecular Biosciences, 2024‏ - frontiersin.org
Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting
approximately 16.5% of pregnancies worldwide and causing significant health concerns …

Resistance patterns, virulence determinants, and biofilm genes of multidrug-resistant Pseudomonas aeruginosa isolated from fish and fish handlers

RMM Abou Elez, EMF Zahra, RMA Gharieb… - Scientific Reports, 2024‏ - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacterium that is widely
distributed in aquatic environments and causes major economic losses in fish and public …

[HTML][HTML] Exploratory optimisation of a LC-HRMS based analytical method for untargeted metabolomic screening of Cannabis Sativa L. through Data Mining

M San Nicolas, A Villate, M Olivares, N Etxebarria… - Analytica Chimica …, 2023‏ - Elsevier
Background Recent increase in public acceptance of cannabis as a natural medical
alternative for certain neurological pathologies has led to its approval in different regions of …

Exploring the potential nutritional benefits of Arthrospira maxima and Chlorella vulgaris: A focus on vitamin B12, amino acids, and micronutrients

M Durdakova, M Kolackova, A Ridoskova, N Cernei… - Food Chemistry, 2024‏ - Elsevier
Abstract Arthrospira (Limnospira) maxima (A. maxima) and Chlorella vulgaris (Ch. vulgaris)
are among the approved microalgae and cyanobacteria (MaC) in the food industry that are …

MetaboAnalystR 4.0: a unified LC-MS workflow for global metabolomics

Z Pang, L Xu, C Viau, Y Lu, R Salavati, N Basu… - Nature …, 2024‏ - nature.com
The wide applications of liquid chromatography-mass spectrometry (LC-MS) in untargeted
metabolomics demand an easy-to-use, comprehensive computational workflow to support …

[HTML][HTML] Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate

G Astre, T Atlan, U Goshtchevsky, A Oron-Gottesman… - Developmental Cell, 2023‏ - cell.com
During aging, the loss of metabolic homeostasis drives a myriad of pathologies. A central
regulator of cellular energy, the AMP-activated protein kinase (AMPK), orchestrates …

The impact of breastfeeding on the preterm infant's microbiome and metabolome: a pilot study

K Schulkers Escalante, SS Bai-Tong, SM Allard… - Pediatric …, 2024‏ - nature.com
Background Human milk is unquestionably beneficial for preterm infants. We investigated
how the transition from tube to oral/breastfeeding impacts the preterm infants' oral and gut …

The keystone gut species Christensenella minuta boosts gut microbial biomass and voluntary physical activity in mice

T Akbuğa-Schön, TA Suzuki, D Jakob, DL Vu… - Mbio, 2024‏ - Am Soc Microbiol
The gut bacteria of the family Christensenellaceae are consistently associated with
metabolic health, but their role in promoting host health is not fully understood. Here, we …