Triazole hybrid compounds: A new frontier in malaria treatment
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …
compounds stands out as a groundbreaking development. Combining the advantages of …
[HTML][HTML] The fate of heterogeneous catalysis & click chemistry for 1, 2, 3-triazoles: Nobel prize in chemistry 2022
The demand for environmental friendly methodologies had shifted the the approach of
scientific community for using easy and green reaction conditions instead of using …
scientific community for using easy and green reaction conditions instead of using …
An updated review on diverse range of biological activities of 1, 2, 4-triazole derivatives: Insight into structure activity relationship
Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …
Emerging impact of triazoles as anti-tubercular agent
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …
compound by combining two or more pharmacophoric units. Being a linkage process, it …
Synthesis, antimicrobial, antibiofilm and computational studies of isatin-semicarbazone tethered 1, 2, 3-triazoles
In present era, heterocyclic compounds containing two or three nitrogen atoms play a vital
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …
Rationale design, synthesis, cytotoxicity evaluation, and in silico mechanistic studies of novel 1, 2, 3-triazoles with potential anticancer activity
A new set of 1, 2, 3-triazoles was designed and synthesized to evaluate their potential to
inhibit the growth of cancer cells. Thiazole, thiazolone, and hydrazine as effective fragments …
inhibit the growth of cancer cells. Thiazole, thiazolone, and hydrazine as effective fragments …
A mini review on pharmacological significance of isatin-1, 2, 3-triazole hybrids
Molecular hybridization is one of the recent stratagems in medicinal chemistry to synthesize
a novel hybrid molecule having better affinity and efficacy by combining two or more …
a novel hybrid molecule having better affinity and efficacy by combining two or more …
1, 2, 3-triazole clubbed and dichloro substituted novel aurones as potential anticancer agents targeting digestive enzymes: design, synthesis, DFT, ADME and …
In the present investigation, we engineered some 1, 2, 3-triazole clubbed and dichloro
substituted novel aurones as potential anticancer agents well capable of targeting digestive …
substituted novel aurones as potential anticancer agents well capable of targeting digestive …
Synthesis, antimicrobial activity and molecular docking of novel benzimidazole conjugated 1, 2, 3-triazole analogues
V Mallikanti, V Thumma, R Matta, KR Valluru… - Chemical Data …, 2023 - Elsevier
A library of novel benzimidazole based 1, 2, 3-triazoles were synthesized by a series of
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …