A reference cell tree will serve science better than a reference cell atlas
Single-cell biology is facing a crisis of sorts. Vast numbers of single-cell molecular profiles
are being generated, clustered and annotated. However, this is overwhelmingly ad hoc, and …
are being generated, clustered and annotated. However, this is overwhelmingly ad hoc, and …
Inference and applications of ancestral recombination graphs
Ancestral recombination graphs (ARGs) summarize the complex genealogical relationships
between individuals represented in a sample of DNA sequences. Their use is currently …
between individuals represented in a sample of DNA sequences. Their use is currently …
Learning the protein language: Evolution, structure, and function
Language models have recently emerged as a powerful machine-learning approach for
distilling information from massive protein sequence databases. From readily available …
distilling information from massive protein sequence databases. From readily available …
[BUCH][B] Handbook of approximate Bayesian computation
As the world becomes increasingly complex, so do the statistical models required to analyse
the challenging problems ahead. For the very first time in a single volume, the Handbook of …
the challenging problems ahead. For the very first time in a single volume, the Handbook of …
Delimiting species using single-locus data and the Generalized Mixed Yule Coalescent approach: a revised method and evaluation on simulated data sets
DNA barcoding-type studies assemble single-locus data from large samples of individuals
and species, and have provided new kinds of data for evolutionary surveys of diversity. An …
and species, and have provided new kinds of data for evolutionary surveys of diversity. An …
Genetics and the conservation of natural populations: allozymes to genomes
FW Allendorf - 2017 - Wiley Online Library
I consider how the study of genetic variation has influenced efforts to conserve natural
populations over the last 50 years. Studies with allozymes in the 1970s provided the first …
populations over the last 50 years. Studies with allozymes in the 1970s provided the first …
DnaSP v5: a software for comprehensive analysis of DNA polymorphism data
Motivation: DnaSP is a software package for a comprehensive analysis of DNA
polymorphism data. Version 5 implements a number of new features and analytical methods …
polymorphism data. Version 5 implements a number of new features and analytical methods …
[HTML][HTML] Implementing and testing the multispecies coalescent model: a valuable paradigm for phylogenomics
In recent articles published in Molecular Phylogenetics and Evolution, Mark Springer and
John Gatesy (S&G) present numerous criticisms of recent implementations and testing of the …
John Gatesy (S&G) present numerous criticisms of recent implementations and testing of the …
Cancer evolution: mathematical models and computational inference
Cancer is a somatic evolutionary process characterized by the accumulation of mutations,
which contribute to tumor growth, clinical progression, immune escape, and drug resistance …
which contribute to tumor growth, clinical progression, immune escape, and drug resistance …
DnaSP, DNA polymorphism analyses by the coalescent and other methods
J Rozas, JC Sánchez-DelBarrio, X Messeguer… - …, 2003 - academic.oup.com
DnaSP is a software package for the analysis of DNA polymorphism data. Present version
introduces several new modules and features which, among other options allow:(1) …
introduces several new modules and features which, among other options allow:(1) …