Neurochemical regulation of the expression and function of glial fibrillary acidic protein in astrocytes
D Li, X Liu, T Liu, H Liu, L Tong, S Jia, YF Wang - Glia, 2020 - Wiley Online Library
Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …
Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions
The purpose of the current study was to examine the neuroprotective effect of rutin against
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …
Concentrically integrative bioassembly of a three-dimensional black phosphorus nanoscaffold for restoring neurogenesis, angiogenesis, and immune homeostasis
Y Qian, WE Yuan, Y Cheng, Y Yang, X Qu, C Fan - Nano Letters, 2019 - ACS Publications
Black phosphorus is well known for its excellent electromechanical properties. Although it
has previously been used for therapeutic drug delivery in cancer, it has never been applied …
has previously been used for therapeutic drug delivery in cancer, it has never been applied …
Role of FABP7 in tumor cell signaling
Lipids are major molecules for the function of organisms and are involved in the
pathophysiology of various diseases. Fatty acids (FAs) signaling and their metabolism are …
pathophysiology of various diseases. Fatty acids (FAs) signaling and their metabolism are …
Intranasal insulin improves mitochondrial function and attenuates motor deficits in a rat 6‐OHDA model of Parkinson's disease
Aims Experimental and clinical evidences demonstrate that common dysregulated pathways
are involved in Parkinson's disease (PD) and type 2 diabetes. Recently, insulin treatment …
are involved in Parkinson's disease (PD) and type 2 diabetes. Recently, insulin treatment …
The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial‐to‐mesenchymal transition and lipid‐derived energy production in prostate …
Early stage localized prostate cancer (PCa) has an excellent prognosis; however, patient
survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying …
survival drops dramatically when PCa metastasizes. The molecular mechanisms underlying …
Omega-3 polyunsaturated fatty acid eicosapentaenoic acid or docosahexaenoic acid improved ageing-associated cognitive decline by regulating glial polarization
J **a, L Yang, C Huang, S Deng, Z Yang, Y Zhang… - Marine Drugs, 2023 - mdpi.com
Neuroinflammation induced by microglial and astrocyte polarizations may contribute to
neurodegeneration and cognitive impairment. Omega (n)-3 polyunsaturated fatty acids …
neurodegeneration and cognitive impairment. Omega (n)-3 polyunsaturated fatty acids …
Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma
L Huang, S Garrett Injac, K Cui, F Braun, Q Lin… - Science translational …, 2018 - science.org
Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Although
outcomes have improved in recent decades, new treatments are still needed to improve …
outcomes have improved in recent decades, new treatments are still needed to improve …
A Dichotomous role for FABP7 in sleep and Alzheimer's disease pathogenesis: a hypothesis
H Needham, G Torpey, CC Flores, CJ Davis… - Frontiers in …, 2022 - frontiersin.org
Fatty acid binding proteins (FABPs) are a family of intracellular lipid chaperone proteins
known to play critical roles in the regulation of fatty acid uptake and transport as well as …
known to play critical roles in the regulation of fatty acid uptake and transport as well as …
Hypothyroidism induces interleukin-1-dependent autophagy mechanism as a key mediator of hippocampal neuronal apoptosis and cognitive decline in postnatal rats
Thyroid hormone (TH) is essential for brain development, and hypothyroidism induces
cognitive deficits in children and young adults. However, the participating mechanisms …
cognitive deficits in children and young adults. However, the participating mechanisms …