Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

Monitoring antibiotic resistance genes in wastewater treatment: Current strategies and future challenges

AQ Nguyen, HP Vu, LN Nguyen, Q Wang… - Science of the Total …, 2021 - Elsevier
Antimicrobial resistance (AMR) is a growing threat to human and animal health. Progress in
molecular biology has revealed new and significant challenges for AMR mitigation given the …

Different microplastics distinctively enriched the antibiotic resistance genes in anaerobic sludge digestion through shifting specific hosts and promoting horizontal …

T Luo, X Dai, Z Chen, L Wu, W Wei, Q Xu, BJ Ni - Water Research, 2023 - Elsevier
Both microplastics (MPs) and antibiotic resistance genes (ARGs) are intensively detected in
waste activated sludge (WAS). However, the distinctive impacts of different MPs on ARGs …

Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge

D Dai, C Brown, H Bürgmann, DGJ Larsson, I Nambi… - Microbiome, 2022 - Springer
Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …

The current burden of carbapenemases: review of significant properties and dissemination among gram-negative bacteria

D Hammoudi Halat, C Ayoub Moubareck - Antibiotics, 2020 - mdpi.com
Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Wastewater treatment plants, an “escape gate” for ESCAPE pathogens

LG Marutescu, M Popa, I Gheorghe-Barbu… - Frontiers in …, 2023 - frontiersin.org
Antibiotics are an essential tool of modern medicine, contributing to significantly decreasing
mortality and morbidity rates from infectious diseases. However, persistent misuse of these …

Complex microbial nitrogen-cycling networks in three distinct anammox-inoculated wastewater treatment systems

Y Yang, J Pan, Z Zhou, J Wu, Y Liu, JG Lin, Y Hong… - Water research, 2020 - Elsevier
Microbial nitrogen removal mediated by anaerobic ammonium oxidation (anammox) are
cost-effective, yet it is time-consuming to accumulate the slow-growing anammox bacteria in …

Metagenomic profiles and health risks of pathogens and antibiotic resistance genes in various industrial wastewaters and the associated receiving surface water

Y Tang, Z Liang, G Li, H Zhao, T An - Chemosphere, 2021 - Elsevier
The aquatic environment may represent an essential route for transmission of antibiotic
resistance to opportunistic human pathogens. Since industrial wastewater is discharged into …

[HTML][HTML] Exploration of the antibiotic resistome in a wastewater treatment plant by a nine-year longitudinal metagenomic study

X Yin, Y Deng, L Ma, Y Wang, LYL Chan… - Environment international, 2019 - Elsevier
The spread of antibiotic resistance genes (ARGs) is a growing global problem. Activated
sludge (AS) in wastewater treatment plants (WWTPs) has been proposed as a hotspot for …

Deciphering extracellular antibiotic resistance genes (eARGs) in activated sludge by metagenome

S Zhou, Y Zhu, Y Yan, W Wang, Y Wang - Water research, 2019 - Elsevier
Antibiotic resistance genes (ARGs) including extracellular ARGs (eARGs) and intracellular
ARGs (iARGs), are recognized as emerging environmental contaminants. Despite extensive …