Genetic aspects of gastric cancer instability
P Hudler - The Scientific World Journal, 2012 - Wiley Online Library
Unravelling the molecular mechanisms underlying gastric carcinogenesis is one of the
major challenges in cancer genomics. Gastric cancer is a very complex and heterogeneous …
major challenges in cancer genomics. Gastric cancer is a very complex and heterogeneous …
Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk
B Karahalil, VA Bohr… - Human & experimental …, 2012 - journals.sagepub.com
Genetic variation in DNA repair genes can modulate DNA repair capacity and may be
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …
Single nucleotide polymorphisms in DNA repair genes and putative cancer risk
B Köberle, B Koch, BM Fischer, A Hartwig - Archives of toxicology, 2016 - Springer
Single nucleotide polymorphisms (SNPs) are the most frequent type of genetic alterations
between individuals. An SNP located within the coding sequence of a gene may lead to an …
between individuals. An SNP located within the coding sequence of a gene may lead to an …
The role of XPC: implications in cancer and oxidative DNA damage
JPM Melis, M Luijten, LHF Mullenders… - … Research/Reviews in …, 2011 - Elsevier
The accumulation of DNA damage is a slow but hazardous phenomenon that may lead to
cell death, accelerated aging features and cancer. One of the most versatile and important …
cell death, accelerated aging features and cancer. One of the most versatile and important …
Genetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese population
Background Potentially functional polymorphisms can modulate protein activities and host's
DNA repair capacity, thereby influencing cancer susceptibility. The association of the …
DNA repair capacity, thereby influencing cancer susceptibility. The association of the …
Association of XRCC1, XRCC2 and XRCC3 Gene Polymorphism with Esophageal Cancer Risk
J Kaur, V Sambyal, K Guleria, NR Singh… - Clinical and …, 2020 - Taylor & Francis
Aim The X-ray repair cross-complementing (XRCC) gene polymorphisms influence
esophageal carcinogenesis by altering the DNA repair capacity. The present study was …
esophageal carcinogenesis by altering the DNA repair capacity. The present study was …
[HTML][HTML] Helicobacter pylori infection and gastric carcinoma: Not all the strains and patients are alike
N Figura, L Marano, E Moretti… - World journal of …, 2016 - ncbi.nlm.nih.gov
Gastric carcinoma (GC) develops in only 1%-3% of Helicobacter pylori (H. pylori) infected
people. The role in GC formation of the bacterial genotypes, gene polymorphisms and host's …
people. The role in GC formation of the bacterial genotypes, gene polymorphisms and host's …
[HTML][HTML] Role of gene polymorphisms in gastric cancer and its precursor lesions: current knowledge and perspectives in Latin American countries
MA Chiurillo - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Latin America shows one of the highest incidence rates of gastric cancer in the world, with
variations in mortality rates among nations or even within countries belonging to this region …
variations in mortality rates among nations or even within countries belonging to this region …
Potentially Functional Variants of PLCE1 Identified by GWASs Contribute to Gastric Adenocarcinoma Susceptibility in an Eastern Chinese Population
M Wang, R Zhang, J He, L Qiu, J Li, Y Wang, M Sun… - PloS one, 2012 - journals.plos.org
Background Recent genome-wide association studies (GWAS) have found a single
nucleotide polymorphism (SNP, rs2274223 A> G) in PLCE1 to be associated with risk of …
nucleotide polymorphism (SNP, rs2274223 A> G) in PLCE1 to be associated with risk of …
The effect of XPD/ERCC2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis
H Xue, Y Lu, B Lin, J Chen, F Tang, G Huang - 2012 - journals.plos.org
Background Potential xeroderma pigmentosum group D (XPD), also called excision repair
cross-complimentary group two (ERCC2), Lys751Gln and Asp312Asn polymorphisms have …
cross-complimentary group two (ERCC2), Lys751Gln and Asp312Asn polymorphisms have …