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T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in sha**, tuning, and regulating the autopathogenic T …
T cells that can respond to self-antigens are present in the peripheral immune repertoire of
all healthy individuals. Recently we have found that unmanipulated SJL mice that are highly …
all healthy individuals. Recently we have found that unmanipulated SJL mice that are highly …
Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands
Recent observations of T-cell responses following T-cell receptor (TCR) interaction with
altered peptide ligands have highlighted the complexity of this signalling system. The h …
altered peptide ligands have highlighted the complexity of this signalling system. The h …
TREM2 maintains microglial metabolic fitness in Alzheimer's disease
Elevated risk of develo** Alzheimer's disease (AD) is associated with hypomorphic
variants of TREM2, a surface receptor required for microglial responses to …
variants of TREM2, a surface receptor required for microglial responses to …
Natural killer cells control tumor growth by sensing a growth factor
Many tumors produce platelet-derived growth factor (PDGF)-DD, which promotes cellular
proliferation, epithelial-mesenchymal transition, stromal reaction, and angiogenesis through …
proliferation, epithelial-mesenchymal transition, stromal reaction, and angiogenesis through …
Decreased specific CD8+ T cell cross‐reactivity of antigen recognition following vaccination with Melan‐A peptide
The aim of T cell vaccines is the expansion of antigen‐specific T cells able to confer immune
protection against pathogens or tumors. Although increase in absolute cell numbers, effector …
protection against pathogens or tumors. Although increase in absolute cell numbers, effector …
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER
In cells treated with brefeldin A (BFA), movement of newly synthesized membrane proteins
from the endoplasmic reticulum (ER) to the Golgi apparatus was blocked. Surprisingly, the …
from the endoplasmic reticulum (ER) to the Golgi apparatus was blocked. Surprisingly, the …
Develo** lymph nodes collect CD4+ CD3− LTβ+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells
For a brief period during fetal lymph node organogenesis in mice, lymph node postcapillary
high endothelial venules surprisingly express the Peyer's patch addressin MAdCAM-1. This …
high endothelial venules surprisingly express the Peyer's patch addressin MAdCAM-1. This …
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins
Of 10 distinct cloned DNA copies of mRNAs expressed in T lymphocytes but not in B
lymphocytes and associated with membrane-bound polysomes, one hybridizes to a region …
lymphocytes and associated with membrane-bound polysomes, one hybridizes to a region …
The skeletal muscle chloride channel in dominant and recessive human myotonia
MC Koch, K Steinmeyer, C Lorenz, K Ricker, F Wolf… - Science, 1992 - science.org
Autosomal recessive generalized myotonia (Becker's disease)(GM) and autosomal
dominant myotonia congenita (Thomsen's disease)(MC) are characterized by skeletal …
dominant myotonia congenita (Thomsen's disease)(MC) are characterized by skeletal …
Interaction of Staphylococcus aureus toxin" superantigens" with human T cells.
YW Choi, B Kotzin, L Herron, J Callahan… - Proceedings of the …, 1989 - pnas.org
A modification of the polymerase chain reaction has been used to establish the fact that a
collection of Staphylococcus aureus toxins are" superantigens," each of which interacts with …
collection of Staphylococcus aureus toxins are" superantigens," each of which interacts with …