Normal cognitive aging
CN Harada, MCN Love… - Clinics in geriatric medicine, 2013 - pmc.ncbi.nlm.nih.gov
The number of Americans over the age of 65 is projected to more than double in the next
forty years, increasing from 40.2 million in 2010 to 88.5 million in 2050. 1 It will become …
forty years, increasing from 40.2 million in 2010 to 88.5 million in 2050. 1 It will become …
How does it STAC up? Revisiting the scaffolding theory of aging and cognition
PA Reuter-Lorenz, DC Park - Neuropsychology review, 2014 - Springer
Abstract “The Scaffolding Theory of Aging and Cognition (STAC)”, proposed in 2009, is a
conceptual model of cognitive aging that integrated evidence from structural and functional …
conceptual model of cognitive aging that integrated evidence from structural and functional …
Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of …
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …
consequences of estrogen decline during menopause accelerate neuropathology in …
[HTML][HTML] Health position paper and redox perspectives-disease burden by transportation noise
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …
Normal aging induces changes in the brain and neurodegeneration progress: review of the structural, biochemical, metabolic, cellular, and molecular changes
J Lee, HJ Kim - Frontiers in aging neuroscience, 2022 - frontiersin.org
Aging is accompanied by many changes in brain and contributes to progressive cognitive
decline. In contrast to pathological changes in brain, normal aging brain changes have …
decline. In contrast to pathological changes in brain, normal aging brain changes have …
β-Amyloid burden in healthy aging: regional distribution and cognitive consequences
Objective: Several lines of evidence suggest that pathologic changes underlying Alzheimer
disease (AD) begin years prior to the clinical expression of the disease, underscoring the …
disease (AD) begin years prior to the clinical expression of the disease, underscoring the …
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease
Triggering receptor expressed on myeloid cells 2 (TREM2) sustains microglia response to
brain injury stimuli including apoptotic cells, myelin damage, and amyloid β (Aβ) …
brain injury stimuli including apoptotic cells, myelin damage, and amyloid β (Aβ) …
Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age
Context Purpose in life is associated with a substantially reduced risk of Alzheimer disease
(AD), but the neurobiologic basis of this protective effect remains unknown. Objective To test …
(AD), but the neurobiologic basis of this protective effect remains unknown. Objective To test …
Risk factors for β-amyloid deposition in healthy aging: vascular and genetic effects
Importance Identifying risk factors for increased β-amyloid (Aβ) deposition is important for
targeting individuals most at risk for develo** Alzheimer disease and informing clinical …
targeting individuals most at risk for develo** Alzheimer disease and informing clinical …
The effect of ageing on f MRI: Correction for the confounding effects of vascular reactivity evaluated by joint f MRI and MEG in 335 adults
In functional magnetic resonance imaging (fMRI) research one is typically interested in
neural activity. However, the blood‐oxygenation level‐dependent (BOLD) signal is a …
neural activity. However, the blood‐oxygenation level‐dependent (BOLD) signal is a …