BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy
P Ramesh, JP Medema - Apoptosis, 2020 - Springer
Apoptosis is a form of programmed cell death that is essential for tissue homeostasis. De-
regulation of the balance between proliferation and apoptosis contributes to tumor initiation …
regulation of the balance between proliferation and apoptosis contributes to tumor initiation …
BCL-G: 20 years of research on a non-typical protein from the BCL-2 family
ML Hartman, M Czyz - Cell Death & Differentiation, 2023 - nature.com
Proteins from the BCL-2 family control cell survival and apoptosis in health and disease, and
regulate apoptosis-unrelated cellular processes. BCL-Gonad (BCL-G, also known as BCL2 …
regulate apoptosis-unrelated cellular processes. BCL-Gonad (BCL-G, also known as BCL2 …
Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice
Chronic inflammation of the large intestine is associated with an increased risk of
develo** colorectal cancer (CRC), the second most common cause of cancer-related …
develo** colorectal cancer (CRC), the second most common cause of cancer-related …
Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis
While the significance of acquired genetic abnormalities in the initiation of hepatocellular
carcinoma (HCC) has been established, the role of epigenetic modification remains …
carcinoma (HCC) has been established, the role of epigenetic modification remains …
Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-γ and TNF-α in intestinal epithelial cells
Proteins of the BCL-2 family are evolutionarily conserved modulators of apoptosis that
function as sensors of cellular integrity. Over the past three decades multiple BCL-2 family …
function as sensors of cellular integrity. Over the past three decades multiple BCL-2 family …
Identification of Serum Biomarkers to Monitor Therapeutic Response in Intestinal-Type Gastric Cancer
LF Dagley, J Yousef, A Preaudet, A Loving… - International Journal of …, 2024 - mdpi.com
There are a limited number of clinically useful serum biomarkers to predict tumor onset or
treatment response in gastric cancer (GC). For this reason, we explored the serum proteome …
treatment response in gastric cancer (GC). For this reason, we explored the serum proteome …
Clinical significance of MUC-4 and associated proteins in Pancreatic and Periampullary Cancers
S Rashid, N Singh, S Rashid, P Das, S Gupta… - Pancreas, 2024 - journals.lww.com
Objective This study primarily aimed to assess the expression of MUC-4 in patients with
Pancreatic Ductal Adenocarcinoma (PDAC) as compared with controls and assess its …
Pancreatic Ductal Adenocarcinoma (PDAC) as compared with controls and assess its …
Confocal Endomicroscopy Monitoring of Tumor Formation
A Preaudet, KY Fung, TL Putoczki - Inflammation and Cancer: Methods …, 2023 - Springer
The utilization of preclinical murine models of colorectal cancer (CRC) has been essential to
our understanding of the onset and progression of disease. As the genetic complexity of …
our understanding of the onset and progression of disease. As the genetic complexity of …
Lung Epithelial Regulation of BCL2 Related Protein A1 (BCL2A1) by Coronaviruses (SARS-CoV) and Type I Interferon Signaling
CV Ramana - bioRxiv, 2021 - biorxiv.org
Highly pathogenic respiratory viruses such as 1918 influenza (HIN1) and coronavirus
(SARS-CoV-2) induce significant lung injury with diffuse alveolar damage, capillary leak …
(SARS-CoV-2) induce significant lung injury with diffuse alveolar damage, capillary leak …
Effect of aqueous extract of Origanum vulgare on acute promyelocytic leukemia cell line (HL-60)
A Mohammadi-Gollou, R Mohammadzadeh… - Scientific Journal of …, 2021 - sjku.muk.ac.ir
Materials and Methods: The viability of HL-60 cells under treatment with various doses of
Origanum vulgare extract was assessed by using a cell cytotoxic assay. Then, IC50 …
Origanum vulgare extract was assessed by using a cell cytotoxic assay. Then, IC50 …