Recent developments in nanomaterials-based drug delivery and upgrading treatment of cardiovascular diseases
Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality
worldwide. However, despite the recent developments in the management of CVDs, the …
worldwide. However, despite the recent developments in the management of CVDs, the …
The exosome-mediated PI3K/Akt/mTOR signaling pathway in neurological diseases
As major public health concerns associated with a rapidly growing aging population,
neurodegenerative diseases (NDDs) and neurological diseases are important causes of …
neurodegenerative diseases (NDDs) and neurological diseases are important causes of …
Ligustrazine nanoparticle hitchhiking on neutrophils for enhanced therapy of cerebral ischemia‐reperfusion injury
Ischemic stroke is a refractory disease that endangers human health and safety owing to
cerebral ischemia. Brain ischemia induces a series of inflammatory reactions. Neutrophils …
cerebral ischemia. Brain ischemia induces a series of inflammatory reactions. Neutrophils …
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis
M Liu, L Luo, J Fu, J He, M Chen, Z He, J Jia - Experimental neurology, 2022 - Elsevier
As a primary nonpharmacological tool, exercise training is neuroprotective after
experimental ischemic stroke by relieving neuroinflammation. However, the specific …
experimental ischemic stroke by relieving neuroinflammation. However, the specific …
Current trends and future perspectives of stroke management through integrating health care team and nanodrug delivery strategy
X Han, Y Qin, C Mei, F Jiao… - Frontiers in Cellular …, 2023 - frontiersin.org
Stroke is accounted as the second-most mortality and adult disability factor in worldwide,
while causes the bleeding promptly and lifetime consequences. The employed functional …
while causes the bleeding promptly and lifetime consequences. The employed functional …
Application and utility of liposomal neuroprotective agents and biomimetic nanoparticles for the treatment of ischemic stroke
T Fukuta, N Oku, K Kogure - Pharmaceutics, 2022 - mdpi.com
Ischemic stroke is still one of the leading causes of high mortality and severe disability
worldwide. Therapeutic options for ischemic stroke and subsequent cerebral …
worldwide. Therapeutic options for ischemic stroke and subsequent cerebral …
Gold nanoparticles in neurological diseases: A review of neuroprotection
This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological
diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and …
diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and …
Thrombolytic therapy based on lyophilized platelet-derived nanocarriers for ischemic stroke
M Migliavacca, C Correa-Paz, M Pérez-Mato… - Journal of …, 2024 - Springer
Background Intravenous administration of fibrinolytic drugs, such as recombinant tissue
plasminogen activator (rtPA) is the standard treatment of acute thrombotic diseases …
plasminogen activator (rtPA) is the standard treatment of acute thrombotic diseases …
Snap25 attenuates neuronal injury via reducing ferroptosis in acute ischemic stroke
W Si, B Sun, J Luo, Z Li, Y Dou, Q Wang - Experimental Neurology, 2023 - Elsevier
Due to the limited clinical treatment options for acute ischemic stroke (AIS), there is still an
urgent requirement for in-depth research on the pathogenesis of AIS and the development of …
urgent requirement for in-depth research on the pathogenesis of AIS and the development of …
Involvement of ceramide metabolism in cerebral ischemia
A Ouro, C Correa-Paz, E Maqueda… - Frontiers in Molecular …, 2022 - frontiersin.org
Ischemic stroke, caused by the interruption of blood flow to the brain and subsequent
neuronal death, represents one of the main causes of disability in worldwide. Although …
neuronal death, represents one of the main causes of disability in worldwide. Although …