Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
[HTML][HTML] PI3K signalling in inflammation
PI3Ks regulate several key events in the inflammatory response to damage and infection.
There are four Class I PI3K isoforms (PI3Kα, β, γ, δ), three Class II PI3K isoforms (PI3KC2α …
There are four Class I PI3K isoforms (PI3Kα, β, γ, δ), three Class II PI3K isoforms (PI3KC2α …
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice
Th17 cells accrue in the intestine in response to particular microbes. In rodents, segmented
filamentous bacteria (SFB) induce intestinal Th17 cells, but analogously functioning …
filamentous bacteria (SFB) induce intestinal Th17 cells, but analogously functioning …
Practice parameter for the diagnosis and management of primary immunodeficiency
FA Bonilla, DA Khan, ZK Ballas, J Chinen… - Journal of Allergy and …, 2015 - Elsevier
The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …
Interleukin-17 and innate immunity in infections and chronic inflammation
Abstract Interleukin 17 (IL-17) includes several cytokines among which IL-17A is considered
as one of the major pro-inflammatory cytokine being central to the innate and adaptive …
as one of the major pro-inflammatory cytokine being central to the innate and adaptive …
Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression
In the tumour microenvironment, cancer cells directly interact with both the immune system
and the stroma. It is firmly established that the immune system, historically believed to be a …
and the stroma. It is firmly established that the immune system, historically believed to be a …
Role of innate immune cells in psoriasis
Y Sato, E Ogawa, R Okuyama - International Journal of Molecular …, 2020 - mdpi.com
Psoriasis is a chronic inflammatory skin condition caused by a combination of hereditary and
environmental factors. Its development is closely related to the adaptive immune response. T …
environmental factors. Its development is closely related to the adaptive immune response. T …
IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases
X Song, Y Qian - Cellular signalling, 2013 - Elsevier
Inflammation is the immediate protective response of the body to pathogen invasions,
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …
IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms
HL Ha, H Wang, P Pisitkun, JC Kim… - Proceedings of the …, 2014 - National Acad Sciences
Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte
proliferation and differentiation and by an influx of inflammatory cells. The mechanisms …
proliferation and differentiation and by an influx of inflammatory cells. The mechanisms …
Prevotella Induces the Production of Th17 Cells in the Colon of Mice
Y Huang, J Tang, Z Cai, K Zhou… - Journal of …, 2020 - Wiley Online Library
Th17‐mediated mucosal inflammation is related to increased Prevotella bacterial
abundance. The actual involvement of Prevotella in the development and accumulation of …
abundance. The actual involvement of Prevotella in the development and accumulation of …