Design and challenges of radiopharmaceuticals
K Vermeulen, M Vandamme, G Bormans… - Seminars in nuclear …, 2019 - Elsevier
This review describes general concepts with regard to radiopharmaceuticals for diagnostic
or therapeutic applications that help to understand the specific challenges encountered …
or therapeutic applications that help to understand the specific challenges encountered …
A guide to 90Y radioembolization and its dosimetry
Radioembolization gains continuous traction as a primarily palliative radiation treatment for
hepatic tumours. A form of nuclear medicine therapy, Yttrium-90 containing microspheres …
hepatic tumours. A form of nuclear medicine therapy, Yttrium-90 containing microspheres …
EANM dosimetry committee series on standard operational procedures: a unified methodology for 99mTc-MAA pre- and 90Y peri-therapy dosimetry in liver radioembolization …
The aim of this standard operational procedure is to standardize the methodology employed
for the evaluation of pre-and post-treatment absorbed dose calculations in 90 Y microsphere …
for the evaluation of pre-and post-treatment absorbed dose calculations in 90 Y microsphere …
Voxel-based dosimetry predicting treatment response and related toxicity in HCC patients treated with resin-based Y90 radioembolization: a prospective, single-arm …
N Kokabi, L Arndt-Webster, B Chen, D Brandon… - European Journal of …, 2023 - Springer
Background There is an increasing body of evidence indicating Y90 dose thresholds for
tumor response and treatment-related toxicity. These thresholds are poorly studied in resin …
tumor response and treatment-related toxicity. These thresholds are poorly studied in resin …
Comparative dosimetry between 99mTc-MAA SPECT/CT and 90Y PET/CT in primary and metastatic liver tumors
A Jadoul, C Bernard, P Lovinfosse, L Gérard… - European journal of …, 2020 - Springer
Introduction The aim of this study is to determine whether 99m Tc-MAA SPECT/CT-based
dosimetry could predict the actual absorbed dose in hepatocellular carcinoma (HCC) or liver …
dosimetry could predict the actual absorbed dose in hepatocellular carcinoma (HCC) or liver …
PET-CT post therapy dosimetry in radioembolization with resin 90Y microspheres: comparison with pre-treatment SPECT-CT 99mTc-MAA results
E Richetta, M Pasquino, M Poli, C Cutaia, C Valero… - Physica Medica, 2019 - Elsevier
Resin microspheres radioembolization is an effective treatment for liver tumors when the
surgical option is not feasible. Doses delivered to tumor and normal liver can be assess in …
surgical option is not feasible. Doses delivered to tumor and normal liver can be assess in …
Comparison of Tc-99m MAA planar versus SPECT/CT imaging for lung shunt fraction evaluation prior to Y-90 radioembolization: are we overestimating lung shunt …
Purpose To compare lung shunt fraction (LSF) prior to Y-90 radioembolization calculated
using planar imaging versus SPECT/CT in patients with hepatocellular carcinoma (HCC) …
using planar imaging versus SPECT/CT in patients with hepatocellular carcinoma (HCC) …
Transarterial radioembolization for hepatocellular carcinoma and hepatic metastases: Clinical aspects and dosimetry models
JK Mikell, YK Dewaraja, D Owen - Seminars in radiation oncology, 2020 - Elsevier
Transarterial radioembolization (TARE) with Yttrium-90 (90 Y) microspheres is a liver-
directed therapy for primary and metastatic disease. This manuscript provides a review of …
directed therapy for primary and metastatic disease. This manuscript provides a review of …
Accurate non-tumoral 99mTc-MAA absorbed dose prediction to plan optimized activities in liver radioembolization using resin microspheres
Aim The manufacturers' recommended methods to calculate delivered activities in liver
radioembolization are simplistic and only slightly personalized. Activity planning could also …
radioembolization are simplistic and only slightly personalized. Activity planning could also …
Lung shunt fraction calculation using 99mTc-MAA SPECT/CT imaging for 90Y microsphere selective internal radiation therapy of liver tumors
Background 99m Tc-macroaggregated albumin (99m Tc-MAA) scintigraphy is utilized in
treatment planning for Yttrium-90 (90 Y) Selective Internal Radiation Therapy (SIRT) of liver …
treatment planning for Yttrium-90 (90 Y) Selective Internal Radiation Therapy (SIRT) of liver …