Lung cancer (LC), the leading cause of cancer-related deaths worldwide, is a complex and
highly heterogeneous disease. Additional to its biological complexity, LC patients are often …

Highlights•Lung cancer in adolescents and young adults (AYA) has specific features that
may unveil a unique genomic background.•AYA harbor a higher percent of oncogenic …

The ALK receptor tyrosine kinase (ALK) gene encodes a transmembrane protein rearranged
in 2–7% of non-small cell lung cancer (NSCLC) cases. This gene has become the second …

To explore the epidemiological characteristics and prognosis of lung cancer in patients aged
under 45 years old in northern China. The population-based database about lung cancer …

Cancer was previously thought to be an inevitable aspect of human health with no effective
treatments. However, the results of in-depth cancer research suggest that most types of …

Background Occurrence at a younger age has been demonstrated to be associated with a
distinct biology in non‐small cell lung cancer. However, genomics and clinical …

Introduction We aimed to assess the magnitude, temporal trends and socioeconomic
disparity in the global burden of tracheal, bronchus and lung (TBL) from 1990 to 2017, using …

Introduction Younger patients with non-small cell lung cancer (NSCLC)(< 50 years)
represent a significant patient population with distinct clinicopathological features and …

Background We describe the clinical features, genetic profile, and their correlation in
NSCLC patients. Methods A total of 256 Chinese patients with NSCLC were enrolled in this …

There is still limited comprehensive genoty** data about young patients with lung
adenocarcinoma. Herein, next generation sequencing (NGS) data of lung adenocarcinoma …