[HTML][HTML] Pyrrolizidine alkaloids—Pros and cons for pharmaceutical and medical applications

K Jayawickreme, D Świstak, E Ozimek… - International Journal of …, 2023 - mdpi.com
Heterocyclic organic compounds named pyrrolizidine alkaloids (PAs) belong to a group of
alkaloids and are synthesized by either plants or microorganisms. Therefore, they are …

[HTML][HTML] Modeling HepaRG metabolome responses to pyrrolizidine alkaloid exposure for insight into points of departure and modes of action

E Dubreil, K Darney, ML Delignette-Muller… - Journal of Hazardous …, 2024 - Elsevier
The new challenges in toxicology demand novel and innovative in vitro approaches for
deriving points of departure (PODs) and determining the mode of action (MOA) of chemicals …

Analysis of potential risks of clinical application of Yi Dian Hong and its proprietary Chinese medicines: A review

G Chen, L Mao, H **a, L Zhu, J Huang, Y Lu, X Liu… - Medicine, 2024 - journals.lww.com
Abstract Yi Dian Hong, belonging to the Asteraceae family, finds widespread use in
traditional Chinese medicine for its effectiveness in clearing heat, detoxifying, promoting …