Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the
artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum …

Background Efficient allocation of resources to intervene against malaria requires a detailed
understanding of the contemporary spatial distribution of malaria risk. It is exactly 40 y since …

Abstract Background: The Lives Saved Tool (LiST) model was developed to estimate the
impact of the scale-up of child survival interventions on child mortality. New advances in …

Drug combination therapies have been devised to delay the development and spread of
resistant malaria parasites. However, poor design often leads to ineffective combinations …

Background Although the molecular basis of resistance to a number of common antimalarial
drugs is well known, a geographic description of the emergence and dispersal of resistance …

Background An assessment of the accuracy of Paracheck Pf®, a malaria rapid diagnostic
test (RDT) detecting histidine rich protein 2 was undertaken amongst children aged 6–59 …

Background Individual patient data (IPD) meta‐analysis is the gold standard. Aggregate
data (AD) and IPD can be combined using conventional pairwise meta‐analysis when IPD …

Background Artesunate and amodiaquine (AS&AQ) is at present the world's second most
widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the …

Background. The development of novel artemisinin-combination therapies suitable for the
treatment of pediatric patients suffering from malaria is a research priority. The aim of this …

We conducted a randomized single-blinded trial comparing the efficacy and safety of
artesunate (AS)+ amodiaquine (AQ, 3 days) versus AS (3 days)+ sulfadoxine …