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Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes
LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
Simvastatin in critically ill patients with Covid-19
REMAP-CAP Investigators - New England Journal of Medicine, 2023 - Mass Medical Soc
Background The efficacy of simvastatin in critically ill patients with coronavirus disease 2019
(Covid-19) is unclear. Methods In an ongoing international, multifactorial, adaptive platform …
(Covid-19) is unclear. Methods In an ongoing international, multifactorial, adaptive platform …
Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials
Background In sepsis and acute respiratory distress syndrome (ARDS), heterogeneity has
contributed to difficulty identifying effective pharmacotherapies. In ARDS, two molecular …
contributed to difficulty identifying effective pharmacotherapies. In ARDS, two molecular …
Practitioner's guide to latent class analysis: methodological considerations and common pitfalls
Latent class analysis is a probabilistic modeling algorithm that allows clustering of data and
statistical inference. There has been a recent upsurge in the application of latent class …
statistical inference. There has been a recent upsurge in the application of latent class …
In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19
Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk …
Biological phenoty** in sepsis and acute respiratory distress syndrome
P Sinha, NJ Meyer, CS Calfee - Annual review of medicine, 2023 - annualreviews.org
Heterogeneity in sepsis and acute respiratory distress syndrome (ARDS) is increasingly
being recognized as one of the principal barriers to finding efficacious targeted therapies …
being recognized as one of the principal barriers to finding efficacious targeted therapies …
Personalized mechanical ventilation in acute respiratory distress syndrome
A personalized mechanical ventilation approach for patients with adult respiratory distress
syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging …
syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging …
COVID-19 for the cardiologist: basic virology, epidemiology, cardiac manifestations, and potential therapeutic strategies
Summary Coronavirus disease-2019 (COVID-19), a contagious disease caused by severe
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has reached pandemic status. As …
acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has reached pandemic status. As …
Pathogenesis of acute respiratory distress syndrome
LA Huppert, MA Matthay… - Seminars in respiratory and …, 2019 - thieme-connect.com
Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …