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RTS, S/AS01 vaccine (Mosquirix™): an overview
MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
[HTML][HTML] Mosquirix™ RTS, S/AS01 vaccine development, immunogenicity, and efficacy
Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)-
infected mosquitoes with a present scale of symptoms ranging from moderate fever to …
infected mosquitoes with a present scale of symptoms ranging from moderate fever to …
Map** functional humoral correlates of protection against malaria challenge following RTS, S/AS01 vaccination
TJ Suscovich, JK Fallon, J Das, AR Demas… - Science Translational …, 2020 - science.org
Vaccine development has the potential to be accelerated by coupling tools such as systems
immunology analyses and controlled human infection models to define the protective …
immunology analyses and controlled human infection models to define the protective …
Host-parasite interactions during Plasmodium infection: Implications for immunotherapies
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the develo** world. Multiple environmental and host and parasite factors govern the …
in the develo** world. Multiple environmental and host and parasite factors govern the …
The road to elimination: current state of schistosomiasis research and progress towards the end game
P Ogongo, RK Nyakundi, GK Chege… - Frontiers in …, 2022 - frontiersin.org
The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of
schistosomiasis as a public health problem. To date, control strategies have focused on …
schistosomiasis as a public health problem. To date, control strategies have focused on …
[HTML][HTML] Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants
Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission
Despite having the highest risk of progressing to severe disease due to lack of acquired
immunity, the youngest children living in areas of highly intense malaria transmission have …
immunity, the youngest children living in areas of highly intense malaria transmission have …
[HTML][HTML] Non-neutralizing functions in anti-SARS-CoV-2 IgG antibodies
S Reinig, SR Shih - Biomedical Journal, 2024 - Elsevier
Most individuals infected with or vaccinated against COVID-19 develop antigenic
neutralizing immunoglobulin G (IgG) antibodies against the SARS-CoV-2 spike protein …
neutralizing immunoglobulin G (IgG) antibodies against the SARS-CoV-2 spike protein …
IgG and IgM responses to the Plasmodium falciparum asexual stage antigens reflect respectively protection against malaria during pregnancy and infanthood
MLE Gbaguidi, R Adamou, S Edslev, A Hansen… - Malaria Journal, 2024 - Springer
Background Plasmodium falciparum malaria is a public health issue mostly seen in tropical
countries. Until now, there is no effective malaria vaccine against antigens specific to the …
countries. Until now, there is no effective malaria vaccine against antigens specific to the …
B‐cell memory in malaria: Myths and realities
B‐cell and antibody responses to Plasmodium spp., the parasite that causes malaria, are
critical for control of parasitemia and associated immunopathology. Antibodies also provide …
critical for control of parasitemia and associated immunopathology. Antibodies also provide …