Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to …

S Hamad, D Derichsweiler, S Papadopoulos… - …, 2019 - pmc.ncbi.nlm.nih.gov
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are promising
candidates to treat myocardial infarction and other cardiac diseases. Such treatments …

Myeloperoxidase mediates postischemic arrhythmogenic ventricular remodeling

M Mollenhauer, K Friedrichs, M Lange… - Circulation …, 2017 - ahajournals.org
Rationale: Ventricular arrhythmias remain the leading cause of death in patients suffering
myocardial ischemia. Myeloperoxidase, a heme enzyme released by polymorphonuclear …

Ascorbic acid induces MLC2v protein expression and promotes ventricular-like cardiomyocyte subtype in human induced pluripotent stem cells derived …

Y Gao, L Su, Y Wei, S Tan, Z Hu, Z Tao… - …, 2023 - pmc.ncbi.nlm.nih.gov
Introduction: The potentially unlimited number of cardiomyocyte (CMs) derived from human
induced pluripotent stem cells (hiPSCs) in vitro facilitates high throughput applications like …

Mechano-pharmacological characterization of cardiomyocytes derived from human induced pluripotent stem cells

M Goßmann, R Frotscher, P Linder… - Cellular Physiology and …, 2016 - karger.com
Abstract Background/Aims: Common systems for the quantification of cellular contraction
rely on animal-based models, complex experimental setups or indirect approaches. The …

Impact of poly (dimethylsiloxane) surface modification with conventional and amino acid-conjugated self-assembled monolayers on the differentiation of induced …

MO Ozturk-Oncel, CO Heras-Bautista… - ACS Biomaterials …, 2021 - ACS Publications
Cardiomyocytes, differentiated from induced pluripotent stem cells (iPSCs), have the
potential to produce patient-and disease-specific pharmacological and toxicological …

(Re-) programming of subtype specific cardiomyocytes

F Hausburg, JJ Jung, M Hoch, M Wolfien… - Advanced Drug Delivery …, 2017 - Elsevier
Adult cardiomyocytes (CMs) possess a highly restricted intrinsic regenerative potential—a
major barrier to the effective treatment of a range of chronic degenerative cardiac disorders …

Vitamin C stimulates human gingival stem cell proliferation and expression of pluripotent markers

P Van Pham, NY Tran, NLC Phan, NB Vu… - In Vitro Cellular & …, 2016 - Springer
Gingival stem cells (GSCs) are a novel source of mesenchymal stem cells (MSCs) that are
easily accessed from the oral cavity. GSCs were considered valuable autograft MSCs with …

β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways

Q Ban, L Qiao, H **a, B **e, J Liu, Y Ma… - American journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Ischemia reperfusion (I/R) injury, an inevitable event accompanying heart transplantation, is
the primary factor leading to organ failure and graft rejection. In order to prevent I/R injury …

[HTML][HTML] Modulation of miRNAs by vitamin C in human bone marrow stromal cells

R Kolhe, AK Mondal, C Pundkar… - Nutrients, 2018 - mdpi.com
MicroRNAs (miRNAs) are small (18–25 nucleotides), noncoding RNAs that have been
identified as potential regulators of bone marrow stromal cell (BMSC) proliferation …

[HTML][HTML] Nucleosome assembly protein 1-like 1 (Nap1l1) regulates the proliferation of murine induced pluripotent stem cells

Y Yan, P Yin, H Gong, Y Xue, G Zhang… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: To investigate whether nucleosome assembly protein 1-like 1 (Nap1l1)
regulates the proliferation of induced pluripotent stem cells (iPSC) and the potential …