Diabetes and infection: review of the epidemiology, mechanisms and principles of treatment

RIG Holt, CS Cockram, RCW Ma, AOY Luk - Diabetologia, 2024 - Springer
An association between diabetes and infection has been recognised for many years, with
infection being an important cause of death and morbidity in people with diabetes. The …

Insulin resistance: Review of the underlying molecular mechanisms

H Yaribeygi, FR Farrokhi, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
Most human cells utilize glucose as the primary substrate, cellular uptake requiring insulin.
Insulin signaling is therefore critical for these tissues. However, decrease in insulin …

Diabetes and multiple long-term conditions: a review of our current global health challenge

K Khunti, YV Chudasama, EW Gregg… - Diabetes …, 2023 - diabetesjournals.org
Use of effective treatments and management programs is leading to longer survival of
people with diabetes. This, in combination with obesity, is thus contributing to a rise in …

HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

[HTML][HTML] Tenofovir alafenamide: a novel prodrug of tenofovir for the treatment of human immunodeficiency virus

AS Ray, MW Fordyce, MJM Hitchcock - Antiviral research, 2016 - Elsevier
Despite substantial progress in the development of antiretroviral regimens that durably
suppress Human Immunodeficiency Virus (HIV) infection, new agents that maintain high …

Obesity and weight gain in persons with HIV

SS Bailin, CL Gabriel, CN Wanjalla… - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The proportion of overweight and obese persons with HIV
(PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to …

Rising obesity prevalence and weight gain among adults starting antiretroviral therapy in the United States and Canada

JR Koethe, CA Jenkins, B Lau… - AIDS research and …, 2016 - liebertpub.com
The proportion of overweight and obese adults in the United States and Canada has
increased over the past decade, but temporal trends in body mass index (BMI) and weight …

Alcohol use and human immunodeficiency virus (HIV) infection: current knowledge, implications, and future directions

EC Williams, JA Hahn, R Saitz, K Bryant… - Alcoholism: Clinical …, 2016 - Wiley Online Library
Alcohol use is common among people living with human immunodeficiency virus (HIV). In
this narrative review, we describe literature regarding alcohol's impact on transmission, care …

Diabetes in sub-saharan africa

JCN Mbanya, AA Motala, E Sobngwi, FK Assah… - The lancet, 2010 - thelancet.com
Summary In Sub-Saharan Africa, prevalence and burden of type 2 diabetes are rising
quickly. Rapid uncontrolled urbanisation and major changes in lifestyle could be driving this …

Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts

BJ Marais, K Lönnroth, SD Lawn… - The Lancet infectious …, 2013 - thelancet.com
Recent data for the global burden of disease reflect major demographic and lifestyle
changes, leading to a rise in non-communicable diseases. Most countries with high levels of …