Microvascular dysfunction in diabetes mellitus and cardiometabolic disease

WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction

EC Kugler, J Greenwood… - Frontiers in Cell and …, 2021 - frontiersin.org
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …

Diabetic microvascular disease: an endocrine society scientific statement

EJ Barrett, Z Liu, M Khamaisi, GL King… - The Journal of …, 2017 - academic.oup.com
Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

R Simo, C Hernández - Trends in Endocrinology & Metabolism, 2014 - cell.com
Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …

[HTML][HTML] Retinal vessel diameters and function in cardiovascular risk and disease

H Hanssen, L Streese, W Vilser - Progress in retinal and eye research, 2022 - Elsevier
In the last two decades evidence has gradually accumulated suggesting that the eye may be
a unique window for cardiovascular risk stratification based on the assessment of subclinical …

[HTML][HTML] Doppler optical coherence tomography

RA Leitgeb, RM Werkmeister, C Blatter… - Progress in retinal and …, 2014 - Elsevier
Abstract Optical Coherence Tomography (OCT) has revolutionized ophthalmology. Since its
introduction in the early 1990s it has continuously improved in terms of speed, resolution …

Optical coherence tomography angiography in diabetes and diabetic retinopathy

J Chua, R Sim, B Tan, D Wong, X Yao, X Liu… - Journal of Clinical …, 2020 - mdpi.com
Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the
retinal microvasculature and is a leading cause of vision loss globally. Recently, optical …

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

R Simo, C Hernandez - Progress in Retinal and eye Research, 2015 - Elsevier
Diabetic retinopathy remains as a leading cause of blindness in developed countries.
Current treatments target late stages of DR when vision has already been significantly …

Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment

SF Abcouwer, TW Gardner - Annals of the New York Academy …, 2014 - Wiley Online Library
Diabetic retinopathy (DR) impairs vision of patients with type 1 and type 2 diabetes,
associated with vascular dysfunction and occlusion, retinal edema, hemorrhage, and …

Cerebral small vessel disease pathology in COVID-19 patients: A systematic review

CD Owens, CB Pinto, S Detwiler, P Mukli… - Ageing Research …, 2023 - Elsevier
Cerebral small vessel disease (CSVD) is the leading cause of vascular cognitive impairment
and is associated with COVID-19. However, contributing factors that often accompany CSVD …