The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …

We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

The majority of disease resistance genes in plants encode nucleotide-binding site leucine-
rich repeat (NBS-LRR) proteins. This large family is encoded by hundreds of diverse genes …

The fibrous collagens are ubiquitous in animals and form the structural basis of all
mammalian connective tissues, including those of the heart, vasculature, skin, cornea …

The preservation of articular cartilage depends on kee** the cartilage architecture intact.
Cartilage strength and function depend on both the properties of the tissue and on their …

Plants are hosts to a wide array of pathogens from all kingdoms of life. In the absence of an
active immune system or combinatorial diversifications that lead to recombination-driven …

Decorin (DCN), an extracellular matrix (ECM) protein, belongs to the small leucine-rich
proteoglycan family. As a pluripotent molecule, DCN regulates the bioactivities of cell growth …

Decorin, a prototype small leucine-rich proteoglycan, regulates a vast array of cellular
processes including collagen fibrillogenesis, wound repair, angiostasis, tumor growth, and …

Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the
collagen family (of which there are 28 types in humans) whose functions are to provide three …

Approximately 500 mya two types of recombinatorial adaptive immune systems appeared in
vertebrates. Jawed vertebrates generate a diverse repertoire of B and T cell antigen …