Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Abstract microRNAs (miRNAs) repress target transcripts through partial complementarity. By
contrast, highly complementary miRNA-binding sites within viral and artificially engineered …

A fundamental principle in biology is that the program for early development is established
during oogenesis in the form of the maternal transcriptome,. How the maternal transcriptome …

Natural killer (NK) cells recognize and kill target cells undergoing different types of stress.
NK cells are also capable of modulating immune responses. In particular, they regulate T …

The fields of applied and translational microRNA research have exploded in recent years as
microRNAs have been implicated across a spectrum of diseases. MicroRNA biomarkers …

Early detection of colorectal cancer is the main prerequisite for successful treatment and
reduction of mortality. Circulating microRNAs were previously identified as promising …

MicroRNAs and tRFs are classes of small non-coding RNAs, known for their roles in
translational regulation of genes. Advances in next-generation sequencing (NGS) have …

Background Next generation sequencing is a key technique in small RNA biology research
that has led to the discovery of functionally different classes of small non-coding RNAs in the …