[HTML][HTML] Genomics to systems biology in animal and veterinary sciences: progress, lessons and opportunities

HN Kadarmideen - Livestock Science, 2014 - Elsevier
Livestock genomics has gone through a paradigm shift since the advent of genome
sequencing that includes Genome-Wide Association Studies (GWAS), Whole Genome …

A novel tumor mutational burden-based risk model predicts prognosis and correlates with immune infiltration in ovarian cancer

H Wang, J Liu, J Yang, Z Wang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Tumor mutational burden (TMB) has been reported to determine the response to
immunotherapy, thus affecting the patient's prognosis in many cancers. However, it is …

Genetic basis of adult migration timing in anadromous steelhead discovered through multivariate association testing

JE Hess, JS Zendt, AR Matala… - Proceedings of the …, 2016 - royalsocietypublishing.org
Migration traits are presumed to be complex and to involve interaction among multiple
genes. We used both univariate analyses and a multivariate random forest (RF) machine …

KIF2C is a novel prognostic biomarker and correlated with immune infiltration in endometrial cancer

L An, J Zhang, D Feng, Y Zhao, W Ouyang… - Stem cells …, 2021 - Wiley Online Library
Endometrial cancer (EC) is commonly diagnosed cancer in women, and the prognosis of
advanced types of EC is extremely poor. Kinesin family member 2C (KIF2C) has been …

Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle

L Koufariotis, YPP Chen, S Bolormaa, BJ Hayes - BMC genomics, 2014 - Springer
Background In livestock, as in humans, the number of genetic variants that can be tested for
association with complex quantitative traits, or used in genomic predictions, is increasing …

Snpdat: Easy and rapid annotation of results from de novo snp discovery projects for model and non-model organisms

AG Doran, CJ Creevey - BMC bioinformatics, 2013 - Springer
Abstract Background Single nucleotide polymorphisms (SNPs) are the most abundant
genetic variant found in vertebrates and invertebrates. SNP discovery has become a highly …

SNP annotation-based whole genomic prediction and selection: an application to feed efficiency and its component traits in pigs

DN Do, LLG Janss, J Jensen… - Journal of Animal …, 2015 - academic.oup.com
The study investigated genetic architecture and predictive ability using genomic annotation
of residual feed intake (RFI) and its component traits (daily feed intake [DFI], ADG, and back …

AgReg-SNPdb: A database of regulatory SNPs for agricultural animal species

S Klees, F Heinrich, AO Schmitt, M Gültas - Biology, 2021 - mdpi.com
Simple Summary Regulatory SNPs (rSNPs) are SNPs located within promoter regions that
have a high potential to alter gene expression by changing the binding affinity of …

[HTML][HTML] Immune-related risk prognostic model for clear cell renal cell carcinoma: Implications for immunotherapy

R Chen, J Wu, S Liu, Y Sun, G Liu, L Zhang, Q Yu, J Xu… - Medicine, 2023 - journals.lww.com
Clear cell renal cell carcinoma (ccRCC) is associated with complex immune interactions. We
conducted a comprehensive analysis of immune-related differentially expressed genes in …

[HTML][HTML] Analysis of tumor mutation burden combined with immune infiltrates in endometrial cancer

J Zhang, L An, X Zhou, R Shi… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Tumor mutational burden (TMB) is widely regarded as a predictor of response
to immunotherapy. Few researchers have focused on the activity and prognosis of TMB in …