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[HTML][HTML] Genomics to systems biology in animal and veterinary sciences: progress, lessons and opportunities
HN Kadarmideen - Livestock Science, 2014 - Elsevier
Livestock genomics has gone through a paradigm shift since the advent of genome
sequencing that includes Genome-Wide Association Studies (GWAS), Whole Genome …
sequencing that includes Genome-Wide Association Studies (GWAS), Whole Genome …
A novel tumor mutational burden-based risk model predicts prognosis and correlates with immune infiltration in ovarian cancer
H Wang, J Liu, J Yang, Z Wang, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Tumor mutational burden (TMB) has been reported to determine the response to
immunotherapy, thus affecting the patient's prognosis in many cancers. However, it is …
immunotherapy, thus affecting the patient's prognosis in many cancers. However, it is …
Genetic basis of adult migration timing in anadromous steelhead discovered through multivariate association testing
JE Hess, JS Zendt, AR Matala… - Proceedings of the …, 2016 - royalsocietypublishing.org
Migration traits are presumed to be complex and to involve interaction among multiple
genes. We used both univariate analyses and a multivariate random forest (RF) machine …
genes. We used both univariate analyses and a multivariate random forest (RF) machine …
KIF2C is a novel prognostic biomarker and correlated with immune infiltration in endometrial cancer
L An, J Zhang, D Feng, Y Zhao, W Ouyang… - Stem cells …, 2021 - Wiley Online Library
Endometrial cancer (EC) is commonly diagnosed cancer in women, and the prognosis of
advanced types of EC is extremely poor. Kinesin family member 2C (KIF2C) has been …
advanced types of EC is extremely poor. Kinesin family member 2C (KIF2C) has been …
Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle
Background In livestock, as in humans, the number of genetic variants that can be tested for
association with complex quantitative traits, or used in genomic predictions, is increasing …
association with complex quantitative traits, or used in genomic predictions, is increasing …
Snpdat: Easy and rapid annotation of results from de novo snp discovery projects for model and non-model organisms
AG Doran, CJ Creevey - BMC bioinformatics, 2013 - Springer
Abstract Background Single nucleotide polymorphisms (SNPs) are the most abundant
genetic variant found in vertebrates and invertebrates. SNP discovery has become a highly …
genetic variant found in vertebrates and invertebrates. SNP discovery has become a highly …
SNP annotation-based whole genomic prediction and selection: an application to feed efficiency and its component traits in pigs
The study investigated genetic architecture and predictive ability using genomic annotation
of residual feed intake (RFI) and its component traits (daily feed intake [DFI], ADG, and back …
of residual feed intake (RFI) and its component traits (daily feed intake [DFI], ADG, and back …
AgReg-SNPdb: A database of regulatory SNPs for agricultural animal species
Simple Summary Regulatory SNPs (rSNPs) are SNPs located within promoter regions that
have a high potential to alter gene expression by changing the binding affinity of …
have a high potential to alter gene expression by changing the binding affinity of …
[HTML][HTML] Immune-related risk prognostic model for clear cell renal cell carcinoma: Implications for immunotherapy
R Chen, J Wu, S Liu, Y Sun, G Liu, L Zhang, Q Yu, J Xu… - Medicine, 2023 - journals.lww.com
Clear cell renal cell carcinoma (ccRCC) is associated with complex immune interactions. We
conducted a comprehensive analysis of immune-related differentially expressed genes in …
conducted a comprehensive analysis of immune-related differentially expressed genes in …
[HTML][HTML] Analysis of tumor mutation burden combined with immune infiltrates in endometrial cancer
J Zhang, L An, X Zhou, R Shi… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Tumor mutational burden (TMB) is widely regarded as a predictor of response
to immunotherapy. Few researchers have focused on the activity and prognosis of TMB in …
to immunotherapy. Few researchers have focused on the activity and prognosis of TMB in …