GM-CSF: A double-edged sword in cancer immunotherapy
A Kumar, A Taghi Khani, A Sanchez Ortiz… - Frontiers in …, 2022 - frontiersin.org
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …
[HTML][HTML] Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases
Angiogenesis is a critical step in the progression of almost all human malignancies and
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …
Macrophages: an inflammatory link between angiogenesis and lymphangiogenesis
Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …
presence of pathology (eg, cancer), and it is these types of environments in which …
Macrophages: a review of their role in wound healing and their therapeutic use
RJ Snyder, J Lantis, RS Kirsner, V Shah… - Wound Repair and …, 2016 - Wiley Online Library
Macrophages are mononuclear phagocytes established during embryogenesis and derived
from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under …
from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under …
Reactive oxygen species and NOX enzymes are emerging as key players in cutaneous wound repair
Our understanding of the role of oxygen in cell physiology has evolved from its long-
recognized importance as an essential factor in oxidative metabolism to its recognition as an …
recognized importance as an essential factor in oxidative metabolism to its recognition as an …
Mesenchymal stem/stromal cell therapy in blood–brain barrier preservation following ischemia: Molecular mechanisms and prospects
PT Do, CC Wu, YH Chiang, CJ Hu… - International journal of …, 2021 - mdpi.com
Ischemic stroke is the leading cause of mortality and long-term disability worldwide.
Disruption of the blood–brain barrier (BBB) is a prominent pathophysiological mechanism …
Disruption of the blood–brain barrier (BBB) is a prominent pathophysiological mechanism …
VCAM-1+ placenta chorionic villi-derived mesenchymal stem cells display potent pro-angiogenic activity
Abstract Introduction Mesenchymal stem cells (MSCs) represent a heterogeneous cell
population that is promising for regenerative medicine. The present study was designed to …
population that is promising for regenerative medicine. The present study was designed to …
Dual gene‐activated dermal scaffolds regulate angiogenesis and wound healing by mediating the coexpression of VEGF and angiopoietin‐1
T Weng, M Yang, W Zhang, R **, S **a… - Bioengineering & …, 2023 - Wiley Online Library
The vascularization of dermal substitutes is a key challenge in efforts to heal deep skin
defects. In this study, dual gene‐activated dermal scaffolds (DGADSs‐1) were fabricated by …
defects. In this study, dual gene‐activated dermal scaffolds (DGADSs‐1) were fabricated by …
The senescence-associated secretory phenotype: Fueling a wound that never heals
T Pulido, MC Velarde, F Alimirah - Mechanisms of Ageing and …, 2021 - Elsevier
Wound healing is impaired with advanced age and certain chronic conditions, such as
diabetes and obesity. Moreover, common cancer treatments, including chemotherapy and …
diabetes and obesity. Moreover, common cancer treatments, including chemotherapy and …
[HTML][HTML] Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats
M O'Hare, G Esquiva, MK McGahon… - JCI insight, 2022 - ncbi.nlm.nih.gov
Loss of retinal blood flow autoregulation is an early feature of diabetes that precedes the
development of clinically recognizable diabetic retinopathy (DR). Retinal blood flow …
development of clinically recognizable diabetic retinopathy (DR). Retinal blood flow …