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[HTML][HTML] Process, material, and regulatory considerations for 3D printed medical devices and tissue constructs
Abstract Three-dimensional (3D) printing is a highly automated platform that facilitates
material deposition in a layer-by-layer approach to fabricate pre-defined 3D complex …
material deposition in a layer-by-layer approach to fabricate pre-defined 3D complex …
Materials strategies to overcome the foreign body response
The foreign body response (FBR) is an immune‐mediated reaction that can occur with most
biomaterials and biomedical devices. The FBR initiates a deterioration in the performance of …
biomaterials and biomedical devices. The FBR initiates a deterioration in the performance of …
Decoding the “fingerprint” of implant materials: insights into the foreign body reaction
Y Chen, Z Luo, W Meng, K Liu, Q Chen, Y Cai, Z Ding… - Small, 2024 - Wiley Online Library
Foreign body reaction (FBR) is a prevalent yet often overlooked pathological phenomenon,
particularly within the field of biomedical implantation. The presence of FBR poses a heavy …
particularly within the field of biomedical implantation. The presence of FBR poses a heavy …
Probing nanotopography-mediated macrophage polarization via integrated machine learning and combinatorial biophysical cue map**
Inflammatory responses, leading to fibrosis and potential host rejection, significantly hinder
the long-term success and widespread adoption of biomedical implants. The ability to …
the long-term success and widespread adoption of biomedical implants. The ability to …
[HTML][HTML] Latest advances: improving the anti-inflammatory and immunomodulatory properties of PEEK materials
Z Zhang, X Zhang, Z Zheng, J **n, S Han, J Qi… - Materials Today Bio, 2023 - Elsevier
Excellent biocompatibility, mechanical properties, chemical stability, and elastic modulus
close to bone tissue make polyetheretherketone (PEEK) a promising orthopedic implant …
close to bone tissue make polyetheretherketone (PEEK) a promising orthopedic implant …
Immunocompatible elastomer with increased resistance to the foreign body response
X Zhou, Z Lu, W Cao, Z Zhu, Y Chen, Y Ni, Z Liu… - Nature …, 2024 - nature.com
Polymeric elastomers are extensively employed to fabricate implantable medical devices.
However, implantation of the elastomers can induce a strong immune rejection known as the …
However, implantation of the elastomers can induce a strong immune rejection known as the …
Releasable, Immune‐Instructive, Bioinspired Multilayer Coating Resists Implant‐Induced Fibrosis while Accelerating Tissue Repair
R Toita, M Kitamura, A Tsuchiya… - Advanced …, 2024 - Wiley Online Library
Implantable biomaterials trigger foreign body reactions (FBRs), which reduces the functional
life of medical devices and prevents effective tissue regeneration. Although existing …
life of medical devices and prevents effective tissue regeneration. Although existing …
Solution Blow Spun Poly (ethylene oxide)/Poly-ε-caprolactone System: Properties and Dissolution in Water
M Lorente, G González-Gaitano, M Valero… - ACS Applied Polymer …, 2023 - ACS Publications
In the present work, fibrous materials based on poly (ethylene oxide)(PEO), poly-ε-
caprolactone (PCL), and a mixture of them (PEO/PCL) have been prepared by solution blow …
caprolactone (PCL), and a mixture of them (PEO/PCL) have been prepared by solution blow …
Cell dynamics and metabolism of the foreign body response: characterizing host-biomaterial interactions for next-generation medical implant biocompatibility
N Callaghan, CA Rempe, Z Froom, K Medd… - Materials …, 2024 - pubs.rsc.org
Implantable medical devices (IMDs) collectively represent a critical mainstay in modern
medicine. Used in many chronic diseases and in acute surgical interventions, IMDs are often …
medicine. Used in many chronic diseases and in acute surgical interventions, IMDs are often …
[HTML][HTML] Bacterial nanocellulose as a simple and tailorable platform for controlled drug release
In this study we present a proof of concept of a simple and straightforward approach for the
development of a Bacterial Nanocellulose drug delivery system (BNC-DDS), envisioning the …
development of a Bacterial Nanocellulose drug delivery system (BNC-DDS), envisioning the …