The implementation of ortho-quinone methide (o-QM) intermediates in complex molecule
assembly represents a remarkably efficient strategy designed by Nature and utilized by …

Berberine bridge enzyme-like oxidases are often involved in natural product biosynthesis
and are seen as essential enzymes for the generation of intricate pharmacophores. These …

Cytochalasans (CYTs), as well as their polycyclic (pcCYTs) and polymerized (meCYTs)
derivatives, constitute one of the largest families of fungal polyketide-nonribosomal peptide …

Oxosorbicillinol and cage-like acresorbicillinol C are bioactive sorbicillinoids produced by
Acremonium chrysogenum. We found that a berberine bridge enzyme-like oxidase AcsorD …

Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin: flavin adenine
dinucleotide (FAD) or flavin mononucleotide (FMN). Flavoproteins are involved in a wide …

Production of phytocannabinoids remains an area of active scientific interest due to the
growing use of cannabis by the public and the underexplored therapeutic potential of the …

4-Hydroxy-2-pyridone alkaloids have attracted attention for synthetic and biosynthetic
studies due to their broad biological activities and structural diversity. Here, we elucidated …

Abstract A bisprenyl naphthoquinone, phytohabinone (1), and a calcimycin congener with
unusual modifications, phytohabimicin (2), were isolated from the culture extract of …

Terrestrial actinomycetes in the genus Streptomyces have long been recognized as prolific
producers of small-molecule natural products, including many clinically important antibiotics …

2, 6-Dimethylphenol (2, 6-DMP) is an environmental pollutant found in industrial wastewater.
Exposure to 2, 6-DMP is of increasing concern as it endangered reportedly some aquatic …