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Oligodendrocytes: Myelination, plasticity, and axonal support
The myelination of axons has evolved to enable fast and efficient transduction of electrical
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …
Structure and neural mechanisms of catatonia
Catatonia is a psychomotor syndrome associated with several psychiatric and medical
conditions. Psychomotor signs range from stupor to agitation, and include pathognomonic …
conditions. Psychomotor signs range from stupor to agitation, and include pathognomonic …
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease
The incidence of Alzheimer's disease (AD), the leading cause of dementia, increases rapidly
with age, but why age constitutes the main risk factor is still poorly understood. Brain ageing …
with age, but why age constitutes the main risk factor is still poorly understood. Brain ageing …
[HTML][HTML] Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease
S Werneburg, J Jung, RB Kunjamma, SK Ha… - Immunity, 2020 - cell.com
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous
system. While work has focused on myelin and axon loss in MS, less is known about …
system. While work has focused on myelin and axon loss in MS, less is known about …
[HTML][HTML] Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment
Chemotherapy results in a frequent yet poorly understood syndrome of long-term
neurological deficits. Neural precursor cell dysfunction and white matter dysfunction are …
neurological deficits. Neural precursor cell dysfunction and white matter dysfunction are …
Noteworthy perspectives on microglia in neuropsychiatric disorders
H Zhu, A Guan, J Liu, L Peng, Z Zhang… - Journal of …, 2023 - Springer
Microglia are so versatile that they not only provide immune surveillance for central nervous
system, but participate in neural circuitry development, brain blood vessels formation, blood …
system, but participate in neural circuitry development, brain blood vessels formation, blood …
Catatonia
Catatonia | New England Journal of Medicine Skip to main content The New England Journal of
Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …
Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …
Activated microglia drive demyelination via CSF1R signaling
Microgliosis is a prominent pathological feature in many neurological diseases including
multiple sclerosis (MS), a progressive auto‐immune demyelinating disorder. The precise …
multiple sclerosis (MS), a progressive auto‐immune demyelinating disorder. The precise …
Catatonia and the immune system: a review
Catatonia is a psychomotor disorder featuring stupor, posturing, and echophenomena. This
Series paper examines the evidence for immune dysregulation in catatonia. Activation of the …
Series paper examines the evidence for immune dysregulation in catatonia. Activation of the …
[HTML][HTML] Catatonia: clinical overview of the diagnosis, treatment, and clinical challenges
AN Edinoff, SE Kaufman, JW Hollier, CG Virgen… - Neurology …, 2021 - mdpi.com
Catatonia is a syndrome that has been associated with several mental illness disorders but
that has also presented as a result of other medical conditions. Schizophrenia and other …
that has also presented as a result of other medical conditions. Schizophrenia and other …