Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …

Head and neck cancer is the sixth most common cancer across the globe. This is generally
associated with tobacco and alcohol consumption. Cancer in the pharynx majorly arises …

Signaling pathways that mediate the normal functions of growth factors are commonly
subverted in cancer. Oncogenes identified by a variety of approaches have been shown to …

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and
behavior. The field has evolved to embrace molecular cytogenetic changes, now termed …

Extracellular signals that promote cell growth activate cascades of protein kinases. The
kinases are dephosphorylated and deactivated by a single type-2A protein phosphatase …

Growth factors and their receptors are involved in the regulation of cell proliferation and also
play a key role in oncogenesis. In this study, a novel putative kinase receptor gene, termed …

Hepatocyte growth factor (HGF) is a peptide-containing multifunctional cytokine that acts on
various epithelial cells to regulate cell growth, movement and morphogenesis, and tissue …