In recent years, significant progress has been made in the studies of the spring-driven
autoinjector, leading to an improved understanding of this device and its interactions with …

The development time of therapeutic monoclonal antibodies (mAbs) has been shortened by
formulation platforms and the assessment of 'protein stability'using 'developability'assays. A …

Cavitation, the formation and collapse of vapor-filled bubbles, poses a problem in spring-
driven autoinjectors (AIs). It occurs when the syringe accelerates abruptly during activation …

Antineoplastic medication compounding is conducted in most large hospitals and involves
the repetitive task of extracting a specific quantity of medication from vials using syringes …

Abrupt acceleration of the syringe of an autoinjector (AI) upon rod-plunger impact may
induce undesired severe cavitation events and impose extraneous stresses upon the …

Understanding the interface motion and hydrodynamic shear induced by the liquid sloshing
during the insertion stage of an autoinjector can help improve drug product administration …

Pressure fluctuations of liquids under short-time acceleration Page 1 J. Fluid Mech. (2025),
vol. 1003, A20, doi:10.1017/jfm.2024.1190 Pressure fluctuations of liquids under short-time …

The pressure wave dynamics and associated cavitation in a water-filled cylinder are studied
experimentally. The use of a double and single-piston apparatus enables the system …

Autoinjectors are pen-like devices that typically deliver drug products of 2 mL or less. They
shield the needle before and after use, reducing patient anxiety from needle phobia and …

Cavitation, liquid slosh, and splashes are ubiquitous in science and engineering. However,
these phenomena are not fully understood. Yet to date, we do not understand when or why …