Nutrients usually act in a coordinated manner in the body. Intestinal absorption and
subsequent metabolism of a particular nutrient, to a certain extent, is dependent on the …

The steroid hormone vitamin D is required for normal calcium and phosphorus metabolism
and is thus an important contributor to musculoskeletal health. Recent data have linked low …

Magnesium is essential for maintaining normal cellular and organ function. In-adequate
magnesium balance is associated with various disorders, such as skeletal deformities …

Appropriate levels of phosphate in the body are maintained by the coordinated regulation of
the bone-derived growth factor FGF23 and the membrane-bound protein Klotho. The …

The increasing prevalence of older-age people in our society represents the culmination of
centuries of medical, scientific, and social endeavors. At least in Western society, now …

Phosphorus is an essential nutrient required for critical biological reactions that maintain the
normal homoeostatic control of the cell. This element is an important component of different …

Identifying factors that accelerate the aging process can provide important therapeutic
targets for slowing down this process. Misregulation of phosphate homeostasis has been …

Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis,
maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as …

Recent advances in single-cell sequencing provide a unique opportunity to gain novel
insights into the diversity, lineage, and functions of cell types constituting a tissue/organ …

Vitamin D is a potent stimulator of monocyte innate immunity, and this effect is mediated via
intracrine conversion of 25‐hydroxyvitamin D (25OHD) to 1, 25‐dihydroxyvitamin D (1, 25 …