Sedentary behaviors (SB) are characterized by low energy expenditure while in a sitting or
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …

Cells of the vascular wall are exquisitely sensitive to changes in their mechanical
environment. In healthy vessels, mechanical forces regulate signaling and gene expression …

Emerging data indicate a substantial decrease in global physical activity levels during the
period of social isolation adopted worldwide to contain the spread of the coronavirus …

Expert recommendations on the assessment of wall shear stress in human coronary arteries:
existing methodologies, technical considerations, and clinical applications | European Heart …

Patient-specific cardiovascular simulation has become a paradigm in cardiovascular
research and is emerging as a powerful tool in basic, translational and clinical research. In …

An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular (CV) risk in
multiple large studies. Careful evaluation of CIMT studies reveals discrepancies in the …

Ischemic stroke, a major cause of mortality in the United States, often contributes to
disruption of the blood-brain barrier (BBB). The BBB along with its supportive cells …