In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within
the body to locally affect the targeted site without damaging intervening tissues. The most …

In transabdominal histotripsy, ultrasound pulses are focused into the body to noninvasively
destroy soft tissues via cavitation. However, the ability to focus is limited by phase …

Hepatocellular carcinoma (HCC), or liver cancer, is one of the fastest growing cancers in the
United States. Current liver ablation methods are thermal based and share limitations …

Recent studies have shown that shockwave heating and millisecond boiling in high-intensity
focused ultrasound fields can result in mechanical fractionation or emulsification of tissue …

Objective: Osteosarcoma (OS) is a devastating primary bone tumor in dogs and humans with
limited non-surgical treatment options. As the first completely non-invasive and non-thermal …

This study demonstrates the ability of histotripsy to generate targeted lesions through the
skullcap without using aberration correction. Histotripsy therapy was delivered using a 500 …

Histotripsy is a non-invasive, non-thermal ablation technique that uses high-amplitude,
focused ultrasound pulses to fractionate tissue via acoustic cavitation. The goal of this study …

This study investigates the feasibility of performing noninvasive histotripsy therapy through
an intact human skull cap. The ablation precision of the therapy using extremely short pulses …

This study investigates the in vivo therapeutic capabilities of transcostal histotripsy without
using aberration correction mechanisms and its thermal impact on overlying tissues. Non …

The goal of this study was to investigate theoretically the effects of nonlinear propagation in
a high-intensity focused ultrasound (HIFU) field produced by a therapeutic phased array and …