During the life of aerobic organisms, the oxygen resulting from numerous reactions is
converted into reactive oxygen species (ROS). Many ROS are dangerous due to their high …

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. MS
pathogenesis is not clear. Destruction of myelin by inflammation caused by autoimmune …

Systemic lupus erythematosus (SLE) is known as a systemic polyethiologic diffuse
autoimmune disease characterized by connective tissue disorganization and the paramount …

We present first evidence showing that some electrophoretically homogeneous IgGs from
the sera of patients with schizophrenia (36.4%) and their Fab and F (ab) 2 fragments as well …

Antibodies (ABs) that target autoantigens were more abundant in the blood of humans and
animals suffering from certain autoimmune and viral diseases than in the blood of healthy …

It is known that intranuclear histones can be pernicious after entering to the extracellular
space. In addition, the immunization of animals with exogenous histones leads to systemic …

Histones play vital roles in chromatin functioning and gene transcription, but in intercellular
space, they are harmful due to stimulating systemic inflammatory and toxic responses …

Histones have a specific key role in the remodeling of chromatin and gene transcription. In
the blood, free histones are damage-connected proteins. Myelin basic protein (MBP) is the …

Histones have vital roles in chromatin functioning and gene transcription. At the same time,
they are pernicious in intercellular space because they stimulate systemic inflammatory and …

Significant importance of autoimmune changes in the pathogenesis of schizophrenia (SCZ)
is not established. Here, we present the first evidence that autoantibodies of 100% SCZ …