All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Objective: The aim was to provide guidelines for evaluation, treatment, and genetic testing
for multiple endocrine neoplasia type 1 (MEN1). Participants: The group, which comprised …

Context: Prevalence data are important for assessing the burden of disease on the health
care system; data on pituitary adenoma prevalence are very scarce. Objective: The objective …

Purpose Non-functioning pituitary adenomas (NFPAs) are benign pituitary neoplasms that
do not cause a hormonal hypersecretory syndrome. An improved understanding of their …

Background Increased secretion of growth hormone leads to gigantism in children and
acromegaly in adults; the genetic causes of gigantism and acromegaly are poorly …

Pituitary adenomas are one of the most frequent intracranial tumors and occur with a
prevalence of approximately 1: 1000 in the developed world. Pituitary adenomas have a …

Context: AIP mutations (AIPmut) give rise to a pituitary adenoma predisposition that occurs
in familial isolated pituitary adenomas and less often in sporadic cases. The clinical and …

Pituitary adenomas are usually benign monoclonal tumours presenting either due to
hypersecretion of pituitary hormones, and/or due to local space occupying effects and …

Hyperprolactinemia is one of the most frequently diagnosed clinical disorders in routine
endocrine practice. Any process interfering with dopamine synthesis, its transport to the …

Context: Familial isolated pituitary adenoma (FIPA) due to aryl hydrocarbon receptor
interacting protein (AIP) gene mutations is an autosomal dominant disease with incomplete …