Dietary sources, health benefits, and risks of caffeine

A Saimaiti, DD Zhou, J Li, RG **ong… - Critical Reviews in …, 2023 - Taylor & Francis
Dietary intake of caffeine has significantly increased in recent years, and beneficial and
harmful effects of caffeine have been extensively studied. This paper reviews antioxidant …

The Pharmacological Potential of Adenosine A2A Receptor Antagonists for Treating Parkinson's Disease

A Mori, JF Chen, S Uchida, C Durlach, SM King… - Molecules, 2022 - mdpi.com
The adenosine A2A receptor subtype is recognized as a non-dopaminergic
pharmacological target for the treatment of neurodegenerative disorders, notably …

Overview of caffeine effects on human health and emerging delivery strategies

SM Saraiva, TA Jacinto, AC Gonçalves, D Gaspar… - Pharmaceuticals, 2023 - mdpi.com
Caffeine is a naturally occurring alkaloid found in various plants. It acts as a stimulant,
antioxidant, anti-inflammatory, and even an aid in pain management, and is found in several …

Current therapeutic targets and multifaceted physiological impacts of caffeine

X Song, N Kirtipal, S Lee, P Malý… - Phytotherapy …, 2023 - Wiley Online Library
Caffeine, which shares consubstantial structural similarity with purine adenosine, has been
demonstrated as a nonselective adenosine receptor antagonist for eliciting most of the …

Adenosinergic pathway in Parkinson's disease: Recent advances and therapeutic perspective

Y Zhao, X Liu, G Yang - Molecular Neurobiology, 2023 - Springer
Parkinson's disease (PD) is a neurodegenerative disease characterized pathologically by α-
synuclein (α-syn) aggregation. In PD, the current mainstay of symptomatic treatment is …

Effect of coffee, tea and alcohol intake on circulating inflammatory cytokines: a two sample-Mendelian randomization study

Y He, S Zhu, Y Zhang, CP Tan, J Zhang… - European Journal of …, 2024 - nature.com
Background Despite the abundance of research examining the effects of coffee, tea, and
alcohol on inflammatory diseases, there is a notable absence of conclusive evidence …

Association of caffeine consumption and brain amyloid positivity in cognitively normal older adults

YB Zheng, J Sun, L Shi, SZ Su, X Chen… - Journal of …, 2023 - content.iospress.com
Background: Several epidemiological studies have reported the protective role of caffeine
on health outcomes; however, it remained debatable on caffeine consumption and brain …

[HTML][HTML] The Potential of Plant Extracts Used in Cosmetic Product Applications—Antioxidants Delivery and Mechanism of Actions

CŞ Gǎlbǎu, M Irimie, AE Neculau, L Dima… - Antioxidants, 2024 - mdpi.com
Natural ingredients have been used in skincare products for thousands of years. The current
focus is on novel natural bioactivities that shield the skin from UV rays and free radicals …

Nutraceuticals Unveiled a Multifaceted Neuroprotective Mechanisms for Parkinson's Disease: Elixir for the Brain

D Soni, S Jamwal, R Chawla, SK Singh… - Food Reviews …, 2024 - Taylor & Francis
Introduction Nutraceuticals are food-derived products offering supplementary health
benefits. These nutraceuticals have been found effective in the treatment of the Parkinson's …

[HTML][HTML] Possible causes of Parkinson's disease

JD Adams - Frontiers in Bioscience-Landmark, 2021 - imrpress.com
Parkinson's disease, in most patients, is possibly caused by natural oxidative stress in
dopaminergic neurons, insufficient exercise and galactose induced oxidative stress …