Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus
L Sommese, A Zullo, FP Mancini, R Fabbricini… - Epigenetics, 2017 - Taylor & Francis
Epigenetics is involved in the altered expression of gene networks that underlie insulin
resistance and insufficiency. Major genes controlling β-cell differentiation and function, such …
resistance and insufficiency. Major genes controlling β-cell differentiation and function, such …
Epigenetic control of β-cell function and failure
Type 2 diabetes is a highly heritable disease, but only∼ 15% of this heritability can be
explained by known genetic variant loci. In fact, body mass index is more predictive of …
explained by known genetic variant loci. In fact, body mass index is more predictive of …
Histone deacetylase inhibitors as antidiabetic agents: Advances and opportunities
M Sonthalia, BS Roy, D Chandrawanshi… - European Journal of …, 2022 - Elsevier
The loss of function or dysfunction of β-cells in the pancreas, attributed to the development of
diabetes, involve alterations in genetic and epigenetic signatures. Recent evidences …
diabetes, involve alterations in genetic and epigenetic signatures. Recent evidences …
Epigenetics and common non communicable disease
MA Tabatabaiefar, RS Sajjadi, S Narrei - Primordial Prevention of Non …, 2019 - Springer
Abstract Common Non communicable diseases (NCDs), such as cardiovascular disease,
cancer, schizophrenia, and diabetes, have become the major cause of death in the world …
cancer, schizophrenia, and diabetes, have become the major cause of death in the world …
HDACs in diabetes: A new era of epigenetic drug
Epigenetics, heritable modifications of gene expression, have been drawing the attention of
researchers for their potential implication in several diseases, including metabolic disorders …
researchers for their potential implication in several diseases, including metabolic disorders …
Biological dogmas in relation to the origin of evolutionary novelties
P Tatemoto, C Guerrero-Bosagna - Origin and evolution of biodiversity, 2018 - Springer
Current evolutionary knowledge emerges influenced by two main currents of thinking. While
some call for more variables to be considered in evolution, others consider that evolutionary …
some call for more variables to be considered in evolution, others consider that evolutionary …