Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that
hypertension is the result of many factors that interact to raise blood pressure and cause end …

Arterial stiffness is an age-related process that is a shared consequence of numerous
diseases including diabetes mellitus (DM), and is an independent predictor of mortality both …

Background: Microvascular damage from large artery stiffness (LAS) in pancreatic, hepatic,
and skeletal muscles may affect glucose homeostasis. Our goal was to evaluate the …

Arterial stiffness is often increased in overweight/obese subjects before the development of
hypertension. It is also one of the earliest indicators of increased cardiovascular disease risk …

We demonstrated the hypothesis that combined exercise improves body composition,
cardiometabolic risk factors, blood pressure (BP), arterial stiffness, and physical functions, in …

Background Aortic pulse wave velocity (PWV) is a measure of arterial stiffness and has
proved useful in predicting cardiovascular morbidity and mortality in several populations of …

Evidence links osteoporosis and cardiovascular disease but the cellular and molecular
mechanisms are unclear. Here we identify skeleton-secreted platelet-derived growth factor …

Background Mechanisms underlying sex differences in heart failure with preserved ejection
fraction (HFpEF) are poorly understood. We sought to examine sex differences in measures …

Background and aims The relation between adiposity and arterial stiffness remains
controversial. We determined whether abdominal and visceral adipose tissue may be a …

Adipokines are active molecules with pleiotropic effects produced by adipose tissue and
involved in obesity-related metabolic and cardiovascular diseases. Arterial stiffness, which is …