SimVascular: an open source pipeline for cardiovascular simulation

A Updegrove, NM Wilson, J Merkow, H Lan… - Annals of biomedical …, 2017 - Springer
Patient-specific cardiovascular simulation has become a paradigm in cardiovascular
research and is emerging as a powerful tool in basic, translational and clinical research. In …

Computational modeling of cardiac hemodynamics: current status and future outlook

R Mittal, JH Seo, V Vedula, YJ Choi, H Liu… - Journal of …, 2016 - Elsevier
The proliferation of four-dimensional imaging technologies, increasing computational
speeds, improved simulation algorithms, and the widespread availability of powerful …

On the choice of outlet boundary conditions for patient-specific analysis of aortic flow using computational fluid dynamics

S Pirola, Z Cheng, OA Jarral, DP O'Regan… - Journal of …, 2017 - Elsevier
Boundary conditions (BCs) are an essential part in computational fluid dynamics (CFD)
simulations of blood flow in large arteries. Although several studies have investigated the …

Learning reduced-order models for cardiovascular simulations with graph neural networks

L Pegolotti, MR Pfaller, NL Rubio, K Ding… - Computers in Biology …, 2024 - Elsevier
Reduced-order models based on physics are a popular choice in cardiovascular modeling
due to their efficiency, but they may experience loss in accuracy when working with …

Automated generation of 0D and 1D reduced‐order models of patient‐specific blood flow

MR Pfaller, J Pham, A Verma, L Pegolotti… - … journal for numerical …, 2022 - Wiley Online Library
Abstract Three‐dimensional (3D) cardiovascular fluid dynamics simulations typically require
hours to days of computing time on a high‐performance computing cluster. One …

Multilevel and multifidelity uncertainty quantification for cardiovascular hemodynamics

CM Fleeter, G Geraci, DE Schiavazzi, AM Kahn… - Computer methods in …, 2020 - Elsevier
Standard approaches for uncertainty quantification in cardiovascular modeling pose
challenges due to the large number of uncertain inputs and the significant computational …

Energetics of blood flow in cardiovascular disease: concept and clinical implications of adverse energetics in patients with a Fontan circulation

FM Rijnberg, MG Hazekamp, JJ Wentzel… - Circulation, 2018 - Am Heart Assoc
Visualization and quantification of the adverse effects of distorted blood flow are important
emerging fields in cardiology. Abnormal blood flow patterns can be seen in various …

Multiscale modeling of cardiovascular flows for clinical decision support

AL Marsden… - Applied …, 2015 - asmedigitalcollection.asme.org
Patient-specific cardiovascular simulations can provide clinicians with predictive tools, fill
current gaps in clinical imaging capabilities, and contribute to the fundamental …

A methodological paradigm for patient‐specific multi‐scale CFD simulations: from clinical measurements to parameter estimates for individual analysis

S Pant, B Fabrèges, JF Gerbeau… - … journal for numerical …, 2014 - Wiley Online Library
SUMMARY A new framework for estimation of lumped (for instance, Windkessel) model
parameters from uncertain clinical measurements is presented. The ultimate aim is to …

Cardiovascular models for personalised medicine: Where now and where next?

DR Hose, PV Lawford, W Huberts, LR Hellevik… - Medical engineering & …, 2019 - Elsevier
The aim of this position paper is to provide a brief overview of the current status of
cardiovascular modelling and of the processes required and some of the challenges to be …