Metabolism and functions of copper in brain
IF Scheiber, JFB Mercer, R Dringen - Progress in neurobiology, 2014 - Elsevier
Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …
Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)
The basic role of metal ions including copper, zinc and iron in neurological pathologies is
generally accepted. The relationship between the development of disease and particular …
generally accepted. The relationship between the development of disease and particular …
Facts and fallacies in the debate on glyphosate toxicity
R Mesnage, MN Antoniou - Frontiers in public health, 2017 - frontiersin.org
The safety profile of the herbicide glyphosate and its commercial formulations is
controversial. Reviews have been published by individuals who are consultants and …
controversial. Reviews have been published by individuals who are consultants and …
The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof
Copper ions are indispensible to life and maintaining tight control over the homeostasis of
copper ions in the body is a prerequisite to sustaining health. Aberrations in normal copper …
copper ions in the body is a prerequisite to sustaining health. Aberrations in normal copper …
Manganese (Mn) and iron (Fe): interdependency of transport and regulation
Abstract Manganese (Mn) and iron (Fe) are transition metals that are crucial to the
appropriate growth, development, function, and maintenance of biological organisms …
appropriate growth, development, function, and maintenance of biological organisms …
Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice
Neurodegenerative diseases are associated with a multitude of dysfunctional cellular
pathways. One major contributory factor is a redox stress challenge during the development …
pathways. One major contributory factor is a redox stress challenge during the development …
Manganese matere bonds in biological systems: PDB inspection and DFT calculations
S Burguera, AK Sahu, MJC Romero… - Physical Chemistry …, 2024 - pubs.rsc.org
A Protein Data Bank (PDB) survey has revealed noncovalent contacts involving Mn centres
and protein residues. Their geometrical features are in line with the interaction between low …
and protein residues. Their geometrical features are in line with the interaction between low …
Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases
Neurodegenerative diseases constitute a set of pathological conditions originating from the
slow, irreversible, and systematic cell loss within the various regions of the brain and/or the …
slow, irreversible, and systematic cell loss within the various regions of the brain and/or the …
Neurodegenerative diseases and exposure to the environmental metals Mn, Pb, and Hg
Metal ions appear to play an important role in several neurodegenerative (ND) diseases.
Evidence suggests that metal ions bind directly to causative amyloidogenic proteins and …
Evidence suggests that metal ions bind directly to causative amyloidogenic proteins and …
Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit
T Crépin, A Dias, A Palencia, C Swale… - Journal of …, 2010 - Am Soc Microbiol
Influenza virus polymerase initiates the biosynthesis of its own mRNAs with capped 10-to 13-
nucleotide fragments cleaved from cellular (pre-) mRNAs. Two activities are required for this …
nucleotide fragments cleaved from cellular (pre-) mRNAs. Two activities are required for this …