The roles of extracellular vesicles in the immune system

EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …

Current advances in the biomedical applications of quantum dots: promises and challenges

N Le, K Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Quantum dots (QDs) are a type of nanoparticle with exceptional photobleaching-resistant
fluorescence. They are highly sought after for their potential use in various optical-based …

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

A Ghasemi, A Martinez-Usatorre, L Li, M Hicham… - Nature Cancer, 2024 - nature.com
Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation,
trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested …

The role of extracellular vesicles in circulating tumor cell-mediated distant metastasis

S Guo, J Huang, G Li, W Chen, Z Li, J Lei - Molecular Cancer, 2023 - Springer
Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

Printed divisional optical biochip for multiplex visualizable exosome analysis at point‐of‐care

X Yang, Z Zhang, Y Wu, H Wang, Y Yun… - Advanced …, 2024 - Wiley Online Library
Rapid detection of various exosomes is of great significance in early diagnosis and
postoperative monitoring of cancers. Here, a divisional optical biochip is reported for …

RNA-based liquid biopsy in head and neck cancer

J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Exosomes at the crossroad between therapeutic targets and therapy resistance in head and neck squamous cell carcinoma

A Jangholi, JM Bark, L Kenny, S Vasani, S Rao… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) are aggressive and clinically
challenging tumours that require a multidisciplinary management approach. Despite …

[HTML][HTML] Secretome analysis using Affinity Proteomics and Immunoassays: a focus on Tumor Biology

VM Beutgen, V Shinkevich, J Pörschke… - Molecular & Cellular …, 2024 - Elsevier
The study of the cellular secretome using proteomic techniques continues to capture the
attention of the research community across a broad range of topics in biomedical research …

Dendritic cell cross‐dressing and tumor immunity

A Martinez‐Usatorre, M De Palma - EMBO Molecular Medicine, 2022 - embopress.org
In addition to direct and cross‐presentation, dendritic cells (DCs) can present tumor antigens
(TAs) to T cells via a hitherto poorly understood mechanism called “cross‐dressing.” DC …

Cancer three-dimensional spheroids mimic in vivo tumor features, displaying “inner” extracellular vesicles and vasculogenic mimicry

I Giusti, G Poppa, S D'Ascenzo, L Esposito… - International Journal of …, 2022 - mdpi.com
The role of extracellular vesicles (EVs) as mediators of cell-to-cell communication in cancer
progression is widely recognized. In vitro studies are routinely performed on 2D culture …