Metabolic regulation of kisspeptin—the link between energy balance and reproduction
Hypothalamic kisspeptin neurons serve as the nodal regulatory centre of reproductive
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …
function. These neurons are subjected to a plethora of regulatory factors that ultimately affect …
Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …
their pathophysiological roles are increasingly the subject of investigation. Evidence …
The kisspeptin system in and beyond reproduction: exploring intricate pathways and potential links between endometriosis and polycystic ovary syndrome
Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …
disorders with a significant impact on the health and quality of life of women affected. A …
The emerging therapeutic potential of kisspeptin and neurokinin B
B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024 - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer's disease
Genome-wide association studies (GWASs) have identified genetic loci associated with the
risk of Alzheimer's disease (AD), but the molecular mechanisms by which they confer risk …
risk of Alzheimer's disease (AD), but the molecular mechanisms by which they confer risk …
Targeting hepatic kisspeptin receptor ameliorates nonalcoholic fatty liver disease in a mouse model
Nonalcoholic fatty liver disease (NAFLD), the most common liver disease, has become a
silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type …
silent worldwide pandemic. The incidence of NAFLD correlates with the rise in obesity, type …
Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects
Obesity is one of major risk factors increasing chronic diseases including type II diabetes,
cardiovascular diseases, and hypertension. The effects of epigallocatechin gallate (EGCG) …
cardiovascular diseases, and hypertension. The effects of epigallocatechin gallate (EGCG) …
[HTML][HTML] Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver …
Background & Aims Acute liver failure (ALF) is a life-threatening disease characterised by
high-grade inflammation and immunoparesis, which is associated with a high incidence of …
high-grade inflammation and immunoparesis, which is associated with a high incidence of …
Kisspeptin and polycystic ovary syndrome
R Tang, X Ding, J Zhu - Frontiers in endocrinology, 2019 - frontiersin.org
Although the pathogenesis of Polycystic Ovary Syndrome (PCOS) is still unclear, the
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
The role of glucagon-like peptide-1 in reproduction: from physiology to therapeutic perspective
Abstract BACKGROUND Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs)
have become firmly established in the treatment of type 2 diabetes and obesity, disorders …
have become firmly established in the treatment of type 2 diabetes and obesity, disorders …