Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications
Multicomponent reactions (MCRs) are powerful synthetic tools in which more than two
starting materials couple with each other to form multi-functionalized compounds in a one …
starting materials couple with each other to form multi-functionalized compounds in a one …
Recent advances (2015–2016) in anticancer hybrids
In spite of the development of a large number of novel anticancer drugs over the years,
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
Corrosion inhibition potential of 2-[(5-methylpyrazol-3-yl) methyl] benzimidazole against carbon steel corrosion in 1 M HCl solution: Combining experimental and …
K Chkirate, K Azgaou, H Elmsellem… - Journal of Molecular …, 2021 - Elsevier
The bi-heterocyclic system, namely 2-[(5-methylpyrazol-3-yl) methyl] benzimidazole (MPMB)
has been synthesized and characterized by 1 H and 13 C NMR methods. Its inhibitory …
has been synthesized and characterized by 1 H and 13 C NMR methods. Its inhibitory …
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
Anti-cancer nitrogen-containing heterocyclic compounds
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
Benzimidazole scaffold as anticancer agent: synthetic approaches and structure–activity relationship
Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …
cell growth having the potential to invade or spread to other parts of the body …
Recent development in indole derivatives as anticancer agent: A mechanistic approach
N Devi, K Kaur, A Biharee… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background: Cancer accounts for several deaths each year. There are multiple FDA
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …
approved drugs for cancer treatments. Due to the severe side effects and multiple drug …