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Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis
X Li, S Wei, S Niu, X Ma, H Li, M **g, Y Zhao - Computers in biology and …, 2022 - Elsevier
Abstract Background Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with
potential efficacy in the treatment of sepsis. However, the main components and potential …
potential efficacy in the treatment of sepsis. However, the main components and potential …
Review on natural products databases: where to find data in 2020
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …
last decencies and the interest around them continues to grow incessantly. As a …
[HTML][HTML] Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis
COVID-19 can result in severe lung injury. It remained to be determined why diabetic
individuals with uncontrolled glucose levels are more prone to develop the severe form of …
individuals with uncontrolled glucose levels are more prone to develop the severe form of …
Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
Accumulating evidence suggests that cardiovascular disease (CVD) is associated with an
altered gut microbiome. Our understanding of the underlying mechanisms has been …
altered gut microbiome. Our understanding of the underlying mechanisms has been …
[HTML][HTML] The DisGeNET cytoscape app: Exploring and visualizing disease genomics data
Thanks to the unbiased exploration of genomic variants at large scale, hundreds of
thousands of disease-associated loci have been uncovered. In parallel, network-based …
thousands of disease-associated loci have been uncovered. In parallel, network-based …
Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism
T Vatanen, KS Jabbar, T Ruohtula, J Honkanen… - Cell, 2022 - cell.com
The perinatal period represents a critical window for cognitive and immune system
development, promoted by maternal and infant gut microbiomes and their metabolites. Here …
development, promoted by maternal and infant gut microbiomes and their metabolites. Here …
State of the field in multi-omics research: from computational needs to data mining and sharing
Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine
two or more omics data sets to aid in data analysis, visualization and interpretation to …
two or more omics data sets to aid in data analysis, visualization and interpretation to …
Structure and function of rice hybrid genomes reveal genetic basis and optimal performance of heterosis
Z Gu, J Gong, Z Zhu, Z Li, Q Feng, C Wang, Y Zhao… - Nature Genetics, 2023 - nature.com
Exploitation of crop heterosis is crucial for increasing global agriculture production.
However, the quantitative genomic analysis of heterosis was lacking, and there is currently …
However, the quantitative genomic analysis of heterosis was lacking, and there is currently …
Efficient analysis of toxicity and mechanisms of environmental pollutants with network toxicology and molecular docking strategy: Acetyl tributyl citrate as an example
S Huang - Science of The Total Environment, 2023 - Elsevier
The study aims to promote network toxicology strategy to efficiently investigate the putative
toxicity and underlying molecular mechanisms of environmental pollutants through an …
toxicity and underlying molecular mechanisms of environmental pollutants through an …
LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer
W Luo, J Wang, W Xu, C Ma, F Wan, Y Huang… - Cell death & …, 2021 - nature.com
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and
development in bladder cancer. However, the underlying molecular mechanisms remain …
development in bladder cancer. However, the underlying molecular mechanisms remain …